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DCC(1291-1447) [cytosol]
Stable Identifier
R-HSA-373629
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
DCC's inhibitory C-terminal domain
Icon
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)
Caspase cleavage of DCC (Homo sapiens)
DCC(1291-1447) [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P43146 DCC
Gene Names
DCC, IGDCC1
Chain
signal peptide:1-25, chain:26-1447
Reference Genes
COSMIC (genes):DCC DCC
ENSEMBL:ENSG00000187323 DCC
HGNC:2701 DCC
UCSC:P43146 DCC
Other Identifiers
11740102_at
11747138_a_at
1630
16852389
206939_PM_at
206939_at
238914_PM_at
238914_at
32890_at
3788561
3788562
3788563
3788597
3788598
3788600
3788601
3788606
3788613
3788614
3788615
3788618
3788619
3788630
3788631
3788639
3788641
3788642
3788648
3788649
3788652
3788662
3788663
3788667
3788668
3788674
3788675
3788676
3788677
3788678
3788679
3788680
3788682
3788683
3788684
3788685
3788686
3788687
3788689
3788694
3788695
3788697
3788699
3788703
3788704
3788705
3788706
3788707
3788732
3788734
42075_at
50286_at
8021245
80344_at
84017_at
84675_s_at
85111_at
A_14_P108875
A_14_P117910
A_14_P129665
A_23_P158708
A_24_P937588
GE495034
GE60014
GE897827
GO:0001764
GO:0004888
GO:0005515
GO:0005829
GO:0005886
GO:0006915
GO:0007155
GO:0007409
GO:0007411
GO:0009986
GO:0010977
GO:0012501
GO:0016020
GO:0021965
GO:0030424
GO:0033563
GO:0033564
GO:0044295
GO:0048671
GO:0048870
GO:0060089
GO:0098609
GO:0098685
GO:0098839
GO:0099170
GO:2000171
HMNXSV003035679
Hs.162025.0.A1_3p_at
ILMN_1665748
PH_hs_0022700
TC18000184.hg
X76132_at
g4885174_3p_at
Participates
as an output of
Caspase cleavage of DCC (Homo sapiens)
Other forms of this molecule
p-Y1420-DCC [plasma membrane]
DCC [plasma membrane]
DCC(26-1290) [plasma membrane]
Inferred To
Dcc [cytosol]
(Mus musculus)
Dcc [cytosol]
(Rattus norvegicus)
dcc [cytosol]
(Danio rerio)
dcc [cytosol]
(Xenopus tropicalis)
fra [cytosol]
(Drosophila melanogaster)
unc-40 [cytosol]
(Caenorhabditis elegans)
DCC [cytosol]
(Bos taurus)
DCC [cytosol]
(Canis familiaris)
DCC [cytosol]
(Sus scrofa)
Cross References
ENSEMBL
ENSP00000389140
,
ENST00000442544
OpenTargets
ENSG00000187323
HPA
ENSG00000187323-DCC
PRO
P43146
Pharos - Targets
P43146
GlyGen
P43146
Orphanet
DCC
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95631 NTN1
1
NTN1 [extracellular region]
(R-HSA-373624)
0.702
4
UniProt:Q9HD67 MYO10
1
MYO10 [cytosol]
(R-HSA-593679)
0.65
7
UniProt:P46777 RPL5
1
RPL5 [cytosol]
(R-HSA-72482)
0.612
7
UniProt:P55211 CASP9
5
CASP9(1-416) [cytosol]
(R-HSA-57033)
CASP9(?-315) [cytosol]
(R-HSA-141638)
CASP9(331-416) [cytosol]
(R-HSA-141639)
p-T412-CASP9(1-416) [cytosol]
(R-HSA-9627087)
p-S196-CASP9(1-416) [cytosol]
(R-HSA-198636)
0.589
2
UniProt:P56270 MAZ
0.508
4
UniProt:P46779 RPL28
1
RPL28 [cytosol]
(R-HSA-72444)
0.462
3
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