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ITGB5 [phagocytic vesicle]
Stable Identifier
R-HSA-1236749
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
phagocytic vesicle
Synonyms
Integrin beta-5
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
Cross-presentation of particulate exogenous antigens (phagosomes) (Homo sapiens)
Engulfment of particulate antigen into phagocytic vesicle (Homo sapiens)
DC receptors recognizing apoptotic cells [phagocytic vesicle] (Homo sapiens)
alphaVbeta5 [phagocytic vesicle] (Homo sapiens)
ITGB5 [phagocytic vesicle] (Homo sapiens)
External Reference Information
External Reference
UniProt:P18084 ITGB5
Gene Names
ITGB5
Chain
signal peptide:1-23, chain:24-799
Reference Genes
BioGPS Gene:3693 ITGB5
COSMIC (genes):ITGB5 ITGB5
CTD Gene:3693 ITGB5
dbSNP Gene:3693 ITGB5
ENSEMBL:ENSG00000082781.12 ITGB5
HGNC:6160 ITGB5
KEGG Gene (Homo sapiens):3693 ITGB5
Monarch:3693 ITGB5
NCBI Gene:3693 ITGB5
OMIM:147561 ITGB5
UCSC:P18084 ITGB5
Reference Transcript
RefSeq:NM_002213.4 ITGB5
Other Identifiers
11754810_a_at
16958356
201124_PM_at
201124_at
201125_PM_s_at
201125_s_at
2058_s_at
214020_PM_x_at
2692817
2692818
2692819
2692821
2692823
2692824
2692826
2692827
2692831
2692836
2692840
2692844
2692845
2692848
2692849
2692850
2692853
2692859
2692864
2692865
2692866
2692867
2692868
2692876
3693
39754_at
8090162
A_23_P166633
GE59781
GO:0001618
GO:0005178
GO:0005515
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005886
GO:0005925
GO:0007010
GO:0007155
GO:0007160
GO:0007179
GO:0007229
GO:0008305
GO:0009986
GO:0016020
GO:0016021
GO:0016477
GO:0023052
GO:0030154
GO:0031410
GO:0032991
GO:0033627
GO:0034684
GO:0035987
GO:0038023
GO:0043149
GO:0043226
GO:0043235
GO:0045335
GO:0046718
GO:0048856
GO:0048870
GO:0060089
GO:0070062
GO:0090136
HMNXSV003047937
Hs.149846.0.S2_3p_at
Hs.149846.1.S1_3p_a_at
ILMN_1668374
ILMN_1796755
ILMN_2311166
J05633_at
PH_hs_0009022
TC03001717.hg
X53002_s_at
g4504772_3p_a_at
Participates
as a component of
alphaVbeta5 [phagocytic vesicle] (Homo sapiens)
Other forms of this molecule
ITGB5 [plasma membrane]
Inferred To
Homologues of ITGB5 [phagocytic vesicle]
(Drosophila melanogaster)
Itgb5 [phagocytic vesicle]
(Mus musculus)
ITGB5 [phagocytic vesicle]
(Bos taurus)
ITGB5 [phagocytic vesicle]
(Canis familiaris)
ITGB5 [phagocytic vesicle]
(Danio rerio)
ITGB5 [phagocytic vesicle]
(Gallus gallus)
ITGB5 [phagocytic vesicle]
(Sus scrofa)
ITGB5 [phagocytic vesicle]
(Xenopus tropicalis)
pat-3 [phagocytic vesicle]
(Caenorhabditis elegans)
Itgbn [phagocytic vesicle]
(Drosophila melanogaster)
mys [phagocytic vesicle]
(Drosophila melanogaster)
Cross References
RefSeq
NP_002204.2
Guide to Pharmacology - Targets
2459
OpenTargets
ENSG00000082781
GeneCards
P18084
HPA
ENSG00000082781-ITGB5
Ensembl
ENSG00000082781
,
ENST00000296181
,
ENSP00000296181
PRO
P18084
Pharos - Targets
P18084
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04004 VTN
1
VTN [extracellular region]
(R-HSA-215971)
0.564
2
UniProt:Q9BY76 ANGPTL4
2
ANGPTL4 [extracellular region]
(R-HSA-381271)
ANGPTL4 [extracellular region]
(R-HSA-6784897)
0.564
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q9HD67 MYO10
1
MYO10 [cytosol]
(R-HSA-593679)
0.544
2
UniProt:P97479 Myo7a
1
Myo7a [cytosol]
(R-MMU-9658865)
0.544
8
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