Reactome | TNFSF9 [plasma membrane]

TNFSF9 [plasma membrane]

Stable Identifier

R-HSA-5667144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Tumor necrosis factor ligand superfamily member 9, TNFL9_HUMAN, CD137L

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P41273 TNFSF9

Gene Names

TNFSF9

Chain

chain:1-254

Reference Genes

BioGPS Gene:8744 TNFSF9

COSMIC (genes):TNFSF9 TNFSF9

CTD Gene:8744 TNFSF9

dbSNP Gene:8744 TNFSF9

ENSEMBL:ENSG00000125657 TNFSF9

ENSEMBL_homo_sapiens_GENE:ENSG00000125657.5 TNFSF9

HGNC:11939 TNFSF9

KEGG Gene (Homo sapiens):8744 TNFSF9

Monarch:8744 TNFSF9

NCBI Gene:8744 TNFSF9

OMIM:606182 TNFSF9

UCSC:P41273 TNFSF9

Reference Transcript

RefSeq:NM_003811.3 TNFSF9

Other Identifiers

11735139_at

11735140_at

16857459

206907_PM_at

206907_at

35000_at

3818473

3818474

3818475

3818476

3818477

3818478

3818479

3818480

8025053

8744

A_14_P117442

A_23_P67224

A_24_P5856

A_33_P3397763

GO:0002376

GO:0005102

GO:0005125

GO:0005164

GO:0005515

GO:0005576

GO:0005615

GO:0005886

GO:0006955

GO:0007154

GO:0007155

GO:0007165

GO:0007267

GO:0012501

GO:0016020

GO:0023052

GO:0030154

GO:0032813

GO:0042104

GO:0042129

GO:0042981

GO:0045585

GO:0048018

GO:0048856

GO:0098772

HMNXSV003040717

ILMN_1751464

PH_hs_0000203

TC19000117.hg

U03398_at

g4507608_3p_at

g4507608_3p_x_at

Participates

as a component of

TNFSF9 trimer [plasma membrane] (Homo sapiens)

Inferred To

TNFSF9 [plasma membrane] (Bos taurus)

TNFSF9 [plasma membrane] (Canis familiaris)

TNFSF9 [plasma membrane] (Sus scrofa)

Tnfsf9 [plasma membrane] (Mus musculus)

Tnfsf9 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_003802.1

OpenTargets

ENSG00000125657

HPA

ENSG00000125657-TNFSF9

GeneCards

P41273

Ensembl

ENST00000245817, ENSG00000125657, ENSP00000245817

PRO

P41273

Pharos - Targets

P41273

PDB

6MGP, 6D3N, 2X29, 6A3V, 6MGE, 6CU0, 6FIB, 6CPR, 6BWV

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01375 TNF	5	TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-233) [plasma membrane] (R-HSA-66220)	0.527	2
UniProt:Q6UWB1 IL27RA	4	IL27RA [plasma membrane] (R-HSA-448478) p-Y611-IL27RA [plasma membrane] (R-HSA-8950330) sIL27RA [extracellular region] (R-HSA-8950454) sIL27RA [cytoplasm] (R-HSA-8950653)	0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	3
UniProt:Q6ZMH5 SLC39A5	1	SLC39A5 [plasma membrane] (R-HSA-442360)	0.527	2
UniProt:Q07011 TNFRSF9	1	TNFRSF9 [plasma membrane] (R-HSA-5666996)	0.527	3
UniProt:P32971 TNFSF8	1	TNFSF8 [plasma membrane] (R-HSA-5667148)	0.527	3
UniProt:P09238 MMP10	2	MMP10 [extracellular region] (R-HSA-1442488) MMP10(18-476) [extracellular region] (R-HSA-1604748)	0.527	2