Reactome | ROPN1 [cytosol]

ROPN1 [cytosol]

Stable Identifier

R-HSA-5667048

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ropporin-1A, ROPN1A, Rhophilin-associated protein 1A, Cancer/testis antigen 91, CT91

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
  - Signaling by Rho GTPases (Homo sapiens)
    - RHO GTPase Effectors (Homo sapiens)
      - RHO GTPases Activate Rhotekin and Rhophilins (Homo sapiens)
        
        ROPN1 binds RHOA:GTP:RHPN1 (Homo sapiens)
        
        RHOA:GTP:RHPN1:ROPN1 [plasma membrane] (Homo sapiens)
        
        ROPN1 [cytosol] (Homo sapiens)
        
        ROPN1 [cytosol] (Homo sapiens)
        
        ROPN1 [cytosol] (Homo sapiens)
        
        ROPN1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9HAT0 ROPN1

Gene Names

ROPN1, ROPN1A

Chain

chain:1-212

Reference Genes

BioGPS Gene:54763 ROPN1

COSMIC (genes):ROPN1 ROPN1

CTD Gene:54763 ROPN1

dbSNP Gene:54763 ROPN1

ENSEMBL:ENSG00000065371 ROPN1

HGNC:17692 ROPN1

Monarch:54763 ROPN1

NCBI Gene:54763 ROPN1

UCSC:Q9HAT0 ROPN1

Reference Transcript

Other Identifiers

11727669_at

11727670_s_at

11760726_at

16958335

220425_PM_x_at

220425_x_at

224191_PM_x_at

224191_x_at

231535_PM_x_at

231535_x_at

233203_PM_at

233203_at

2640264

2640266

2640268

2640269

2640271

2640272

2640274

2640275

2640276

2640277

2640279

2692641

2692642

2692643

2692644

2692645

2692646

2692647

2692648

2692649

2692650

2692651

2692655

2692656

2692657

54763

66240_s_at

66429_at

8082261

8090152

86154_at

A_24_P931211

A_32_P184464

A_33_P3328990

GE522680

GE56639

GO:0001932

GO:0005515

GO:0005634

GO:0005737

GO:0005929

GO:0007018

GO:0022414

GO:0030317

GO:0031514

GO:0042802

GO:0043226

GO:0044782

GO:0048240

GO:0048870

GO:0061512

HMNXSV003021812

HMNXSV003043888

HMNXSV003053357

Hs.194093.2.A1_3p_a_at

Hs.194093.3.A1_3p_at

ILMN_1668766

ILMN_1702055

PH_hs_0038592

TC03001715.hg

g11037715_3p_x_at

Participates

as a component of

ROPN1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENST00000479867, ENST00000484329, ENST00000495093, ENSP00000420567, ENST00000620893, ENSP00000184183, ENSP00000483603, ENST00000459660, ENST00000405845, ENSP00000420590, ENST00000184183, ENSP00000419205, ENSP00000417379, ENSP00000385919

OpenTargets

ENSG00000065371

HPA

ENSG00000065371-ROPN1

PRO

Q9HAT0

Pharos - Targets

Q9HAT0

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.781	8
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.718	6
UniProt:P61024 CKS1B	1	CKS1B [nucleoplasm] (R-HSA-187533)	0.718	6
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.718	6
UniProt:Q92917 GPKOW	1	GPKOW [nucleoplasm] (R-HSA-8850839)	0.718	6
UniProt:P24588 AKAP5	2	AKAP5 [plasma membrane] (R-HSA-381669) AKAP5 [cytosol] (R-HSA-416331)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.556	3