AKR1A1 reduces D-glucuronate to L-gulonate

Stable Identifier
R-HSA-5661256
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
D-glucuronate + NADPH + H+ => L-gulonate + NADP+
Locations in the PathwayBrowser
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Cytosolic AKR1A1 (Aldo-keto reductase family 1 member A1) catalyzes the reduction by NADPH of D-glucuronate to L-gulonate (Barski et al. 1995).

Literature References
PubMed ID Title Journal Year
7669785 Mechanism of human aldehyde reductase: characterization of the active site pocket

Barski, OA, Gabbay, KH, Grimshaw, CE, Bohren, KM

Biochemistry 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
L-glucuronate reductase activity of AKR1A1 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created