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BST2 [plasma membrane]
Stable Identifier
R-HSA-5624196
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Bone marrow stromal antigen 2, BST2_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1-host interactions (Homo sapiens)
SARS-CoV-1 activates/modulates innate immune responses (Homo sapiens)
SARS-CoV-1 7a binds BST2 (Homo sapiens)
BST2:BST2 [plasma membrane] (Homo sapiens)
BST2 [plasma membrane] (Homo sapiens)
SARS-CoV-1 7a:BST2 [plasma membrane] (Homo sapiens)
BST2:BST2 [plasma membrane] (Homo sapiens)
BST2 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Expression of IFN-induced genes (Homo sapiens)
BST2 [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule membrane proteins (Homo sapiens)
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
BST2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q10589 BST2
Gene Names
BST2
Chain
chain:1-161, propeptide:162-180
Reference Genes
BioGPS Gene:684 BST2
COSMIC (genes):BST2 BST2
CTD Gene:684 BST2
dbSNP Gene:684 BST2
ENSEMBL:ENSG00000130303 BST2
ENSEMBL_homo_sapiens_GENE:ENSG00000130303.14 BST2
HGNC:1119 BST2
KEGG Gene (Homo sapiens):684 BST2
Monarch:684 BST2
NCBI Gene:684 BST2
OMIM:600534 BST2
UCSC:Q10589 BST2
Reference Transcript
RefSeq:NM_004335.3 BST2
Other Identifiers
11716034_a_at
11716035_at
11716036_x_at
16870200
201641_PM_at
201641_at
3854455
3854457
3854458
3854460
3854462
3854463
3854464
3854465
3854466
39061_at
684
8035304
A_23_P39465
A_33_P3220911
D28137_at
GE61255
GE78965
GO:0002376
GO:0002737
GO:0003723
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005768
GO:0005770
GO:0005771
GO:0005773
GO:0005794
GO:0005886
GO:0007010
GO:0008191
GO:0009615
GO:0009986
GO:0016020
GO:0016324
GO:0023052
GO:0030308
GO:0030336
GO:0031410
GO:0032956
GO:0034341
GO:0035455
GO:0035456
GO:0035577
GO:0042113
GO:0042802
GO:0042803
GO:0043123
GO:0043226
GO:0043231
GO:0045071
GO:0045087
GO:0045121
GO:0048870
GO:0051607
GO:0070062
GO:0070665
GO:0098542
GO:0098552
GO:0098772
GO:1901253
HMNXSV003018253
ILMN_1723480
PH_hs_0006483
TC19001275.hg
g7262372_3p_at
Participates
as a component of
BST2:BST2 [plasma membrane] (Homo sapiens)
as a member of
Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)
as an output of
Expression of IFN-induced genes (Homo sapiens)
Other forms of this molecule
BST2 [azurophil granule membrane]
Inferred To
BST2 [plasma membrane]
(Canis familiaris)
BST2 [plasma membrane]
(Sus scrofa)
LOC618737 [plasma membrane]
(Bos taurus)
Bst2 [plasma membrane]
(Mus musculus)
Bst2 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_004326.1
OpenTargets
ENSG00000130303
HPA
ENSG00000130303-BST2
GeneCards
Q10589
Ensembl
ENSP00000252593
,
ENST00000252593
,
ENSG00000130303
PRO
Q10589
Pharos - Targets
Q10589
PDB
3NWH
,
3MQ9
,
7Q9A
,
2X7A
,
3MQ7
,
6DFF
,
6CRI
,
3MQB
,
3MQC
,
2LK9
,
4P6Z
,
6D83
,
6CM9
,
2XG7
,
6D84
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q10589 BST2
2
BST2 [plasma membrane]
(R-HSA-5624196)
BST2 [azurophil granule membrane]
(R-HSA-6799130)
0.831
10
UniProt:P69699 VPU
0.626
7
UniProt:P60033 CD81
1
CD81 [plasma membrane]
(R-HSA-197933)
0.556
3
UniProt:P59901 LILRA4
1
LILRA4 [plasma membrane]
(R-HSA-6786744)
0.544
2
ChEBI:27363 ZINC ATOM
0.544
2
UniProt:P35585
7
Ap1m1 [cytoplasmic vesicle membrane]
(R-MMU-351196)
Ap1m1 [Golgi membrane]
(R-MMU-350805)
Ap1m1 [lysosomal membrane]
(R-MMU-432708)
Ap1m1 [trans-Golgi network membrane]
(R-MMU-2130512)
Ap1m1 [cytosol]
(R-MMU-167700)
Ap1m1 [plasma membrane]
(R-MMU-6806311)
Ap1m1 [specific granule membrane]
(R-MMU-6799365)
0.527
2
UniProt:A9QPL9 A9QPL9
0.524
2
UniProt:P05923 VPU
0.463
2
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