HOXD4 gene is transcribed

Stable Identifier
R-HSA-5617874
Type
Reaction [omitted]
Species
Homo sapiens
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The HOXD4 gene is transcribed to yield mRNA (Moroni et al. 1993, Morrison et al. 1996, Morrison et al. 1997). In mouse embryos Hoxd4 mRNA is observed in rhombomere 7 and caudally in spinal cord and prevertebrae. The HOXD4 promoter region is a target of the microRNA miR-10a, which causes repression of transcription (Tan et al. 2009).

Literature References
PubMed ID Title Journal Year
7908827 Regulation of the human HOXD4 gene by retinoids

Moroni, MC, Viganó, MA, Mavilio, F

Mech. Dev. 1993
9272954 HOXD4 and regulation of the group 4 paralog genes

Morrison, A, Ariza-McNaughton, L, Gould, A, Featherstone, M, Krumlauf, R

Development 1997
8674428 In vitro and transgenic analysis of a human HOXD4 retinoid-responsive enhancer

Morrison, A, Moroni, MC, Ariza-McNaughton, L, Krumlauf, R, Mavilio, F

Development 1996
19232136 Transcriptional inhibiton of Hoxd4 expression by miRNA-10a in human breast cancer cells

Tan, Y, Zhang, B, Wu, T, Skogerb√ł, G, Zhu, X, Guo, X, He, S, Chen, R

BMC Mol. Biol. 2009
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