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p13S-GLI3:SUFU [ciliary base]
Stable Identifier
R-HSA-5610587
Type
Complex
Species
Homo sapiens
Compartment
ciliary base
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
GLI3 is processed to GLI3R by the proteasome (Homo sapiens)
GSK3 phosphorylates p-GLI3 (Homo sapiens)
p13S-GLI3:SUFU [ciliary base] (Homo sapiens)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Homo sapiens)
p13S-GLI3:SUFU [ciliary base] (Homo sapiens)
Participants
components
p13S-GLI3 [ciliary base] (Homo sapiens)
SUFU [ciliary base] (Homo sapiens)
Participant Of
input
SCF(beta-TrCP) ubiquitinates p-GLI3
output
GSK3 phosphorylates p-GLI3
Inferred To
p13S-GLI3:SUFU [ciliary base] (Bos taurus)
p13S-GLI3:SUFU [ciliary base] (Canis familiaris)
p13S-GLI3:SUFU [ciliary base] (Danio rerio)
p13S-GLI3:SUFU [ciliary base] (Drosophila melanogaster)
p13S-GLI3:SUFU [ciliary base] (Gallus gallus)
p13S-GLI3:SUFU [ciliary base] (Mus musculus)
p13S-GLI3:SUFU [ciliary base] (Rattus norvegicus)
p13S-GLI3:SUFU [ciliary base] (Sus scrofa)
p13S-GLI3:SUFU [ciliary base] (Taeniopygia guttata)
p13S-GLI3:SUFU [ciliary base] (Xenopus tropicalis)
Cross References
ComplexPortal
CPX-150
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