Reactome | KCNIP3 [plasma membrane]

KCNIP3 [plasma membrane]

Stable Identifier

R-HSA-5577044

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Calsenilin, CSEN_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y2W7 KCNIP3

Gene Names

KCNIP3, CSEN, DREAM, KCHIP3

Chain

chain:1-256

Reference Genes

BioGPS Gene:30818 KCNIP3

COSMIC (genes):KCNIP3 KCNIP3

CTD Gene:30818 KCNIP3

dbSNP Gene:30818 KCNIP3

ENSEMBL:ENSG00000115041 KCNIP3

HGNC:15523 KCNIP3

KEGG:hsa:30818 KCNIP3

Monarch:30818 KCNIP3

NCBI Gene:30818 KCNIP3

OMIM:604662 KCNIP3

UCSC:Q9Y2W7 KCNIP3

Reference Transcript

Other Identifiers

11725012_a_at

11753532_a_at

1555694_PM_a_at

1555694_a_at

1569355_PM_at

1569355_at

16882895

228269_3p_x_at

228269_PM_x_at

228269_x_at

231774_PM_at

231774_at

234198_PM_at

234198_at

2493995

2493996

2493997

2494000

2494001

2494002

2494003

2494004

2494005

2494013

2494014

2494015

2494016

2494017

2494018

2494019

2494020

2494024

2494025

2494026

2494033

2494034

2494035

2494043

2494045

2494046

2494048

2494049

2494050

2494051

2494052

2494054

2494055

2494065

30818

59964_at

78854_at

8043552

A_23_P356004

GE611455

GO:0000122

GO:0000978

GO:0001227

GO:0003677

GO:0005215

GO:0005267

GO:0005509

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005794

GO:0005829

GO:0005886

GO:0006355

GO:0006915

GO:0007165

GO:0008076

GO:0012501

GO:0015459

GO:0034702

GO:0043226

GO:0046872

GO:0055085

GO:0071805

GO:0072659

GO:0098772

GO:0140110

GO:1901379

HMNXSV003008568

Hs.13228.0.A1_3p_at

Hs.13228.0.A1_3p_s_at

Hs.13228.0.A1_3p_x_at

Hs.13228.1.S2_3p_at

Hs.306828.0.S1_3p_at

Hs2.13228.2.S1_3p_s_at

Hs2.397926.1.S1_3p_s_at

ILMN_1744403

ILMN_2262644

ILMN_2350823

PH_hs_0023663

TC02000572.hg

Participates

as a member of

KCNIP1-4 [plasma membrane] (Homo sapiens)

Other forms of this molecule

KCNIP3 [nucleoplasm]

Inferred To

ncs-7 [plasma membrane] (Caenorhabditis elegans)

kcnip3b [plasma membrane] (Danio rerio)

CG42683 [plasma membrane] (Drosophila melanogaster)

kcnip3 [plasma membrane] (Xenopus tropicalis)

KCNIP3 [plasma membrane] (Bos taurus)

KCNIP3 [plasma membrane] (Gallus gallus)

KCNIP3 [plasma membrane] (Mus musculus)

KCNIP3 [plasma membrane] (Rattus norvegicus)

KCNIP3 [plasma membrane] (Sus scrofa)

Cross References

ENSEMBL

ENST00000295225, ENST00000468529, ENSP00000417499, ENSP00000295225

OpenTargets

ENSG00000115041

HPA

ENSG00000115041-KCNIP3

PRO

Q9Y2W7

Pharos - Targets

Q9Y2W7

HMDB Protein

HMDBP02787

PDB

2E6W

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N6Q3 CD177	3	CD177 [tertiary granule membrane] (R-HSA-6800187) CD177 [plasma membrane] (R-HSA-202784) CD177 [specific granule membrane] (R-HSA-6800166)	0.781	9
UniProt:P40189 IL6ST	2	p-Y-IL6ST [plasma membrane] (R-HSA-8950439) IL6ST [plasma membrane] (R-HSA-448453)	0.601	7
UniProt:Q7Z434 MAVS	2	MAVS [mitochondrial outer membrane] (R-HSA-913730) K48polyUb-MAVS [mitochondrial outer membrane] (R-HSA-983463)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3
UniProt:P08294 SOD3	3	SOD3 (19-227) [extracellular region] (R-HSA-4837350) SOD3 [extracellular region] (R-HSA-3299690) SOD3 [Golgi lumen] (R-HSA-3697878)	0.556	6
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:O14843 FFAR3	1	FFAR3 [plasma membrane] (R-HSA-443951)	0.556	3

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