Reactome | TAOK3 [cytosol]

TAOK3 [cytosol]

Stable Identifier

R-HSA-5423594

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Serine/threonine-protein kinase TAO3 ecNumber2.7.11.1/ecNumber, TAOK3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9H2K8 TAOK3

Gene Names

TAOK3, DPK, JIK, KDS, MAP3K18

Chain

chain:1-898

Reference Genes

BioGPS Gene:51347 TAOK3

COSMIC (genes):TAOK3 TAOK3

CTD Gene:51347 TAOK3

dbSNP Gene:51347 TAOK3

ENSEMBL:ENSG00000135090 TAOK3

HGNC:18133 TAOK3

KEGG Gene (Homo sapiens):51347 TAOK3

Monarch:51347 TAOK3

NCBI Gene:51347 TAOK3

OMIM:616711 TAOK3

UCSC:Q9H2K8 TAOK3

Reference Transcript

Other Identifiers

11733258_a_at

11733259_s_at

16770961

220761_s_at

3473803

3473804

3473805

3473806

3473807

3473808

3473811

3473817

3473821

3473823

3473824

3473825

3473826

3473827

3473836

3473838

3473839

3473840

3473845

3473846

3473848

3473849

3473852

3473853

3473854

3473855

3473856

3473863

3473864

3473865

3473883

3473887

3473888

3473902

41646_at

51347

67219_at

73951_at

7966851

A_23_P2203

A_24_P104174

A_33_P3346102

GE58717

GO:0000165

GO:0000166

GO:0000278

GO:0000902

GO:0003674

GO:0004672

GO:0004674

GO:0004860

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0006259

GO:0006281

GO:0006464

GO:0006468

GO:0006469

GO:0006950

GO:0006974

GO:0007049

GO:0007095

GO:0007165

GO:0008150

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0030154

GO:0030234

GO:0031098

GO:0032147

GO:0032874

GO:0034641

GO:0043167

GO:0043507

GO:0046329

GO:0046330

GO:0046777

GO:0048812

GO:0048856

GO:0106310

GO:0106311

HMNXSV003034963

HMNXSV003037670

ILMN_3307863

PH_hs_0001129

TC12002018.hg

g6708149_3p_at

g7705559_3p_a_at

Participates

as a candidate of

Inferred To

Homologues of TAOK3 [cytosol] (Dictyostelium discoideum)

taok3a [cytosol] (Danio rerio)

kin-18 [cytosol] (Caenorhabditis elegans)

dst1 [cytosol] (Dictyostelium discoideum)

TAOK3 [cytosol] (Bos taurus)

TAOK3 [cytosol] (Canis familiaris)

TAOK3 [cytosol] (Gallus gallus)

TAOK3 [cytosol] (Sus scrofa)

TAOK3 [cytosol] (Xenopus tropicalis)

Taok3 [cytosol] (Mus musculus)

Taok3 [cytosol] (Rattus norvegicus)

Tao [cytosol] (Drosophila melanogaster)

pakH-2 [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_057365.3, NP_001333417.1, NP_001333418.1

ZINC - World Drugs

TAOK3_HUMAN

Guide to Pharmacology - Targets

2235

OpenTargets

ENSG00000135090

ZINC - FDA approved

TAOK3_HUMAN

ZINC - Substances

TAOK3_HUMAN

ZINC target

Q9H2K8

ZINC - Biogenic

TAOK3_HUMAN

PRO

Q9H2K8

PDB

6BDN

ZINC - Investigational

TAOK3_HUMAN

GeneCards

Q9H2K8

HPA

ENSG00000135090-TAOK3

Ensembl

ENST00000419821, ENSG00000135090, ENST00000392533, ENSP00000376317, ENSP00000416374

Pharos - Targets

Q9H2K8

ZINC - Predictions - Purchasable

TAOK3_HUMAN

HMDB Protein

HMDBP09480

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.524	2
UniProt:O75460 ERN1	2	p-S724-ERN1 [endoplasmic reticulum membrane] (R-HSA-381029) ERN1 [endoplasmic reticulum membrane] (R-HSA-381076)	0.508	3

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