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DHRS3 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-5419172
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Short-chain dehydrogenase/reductase 3 ecNumber1.1.1.300/ecNumber, DHRS3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
RA biosynthesis pathway (Homo sapiens)
RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Homo sapiens)
RDH11,14,DHRS3,DHRS4 [endoplasmic reticulum membrane] (Homo sapiens)
DHRS3 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75911 DHRS3
Gene Names
DHRS3, RDH17, SDR16C1, UNQ2424/PRO4983
Chain
chain:1-302
Reference Genes
BioGPS Gene:9249 DHRS3
COSMIC (genes):DHRS3 DHRS3
CTD Gene:9249 DHRS3
dbSNP Gene:9249 DHRS3
ENSEMBL:ENSG00000162496 DHRS3
ENSEMBL_homo_sapiens_GENE:ENSG00000162496.9 DHRS3
HGNC:17693 DHRS3
KEGG Gene (Homo sapiens):9249 DHRS3
Monarch:9249 DHRS3
NCBI Gene:9249 DHRS3
OMIM:612830 DHRS3
UCSC:O75911 DHRS3
Reference Transcript
RefSeq:NM_004753.6 DHRS3
Other Identifiers
11716835_a_at
11749344_a_at
16681827
202481_PM_at
202481_at
2397026
2397027
2397028
2397029
2397036
2397040
2397041
2397046
2397047
2397072
2397073
2397074
2397075
2397077
2397078
2397079
2397080
40782_at
7912537
9249
A_23_P33759
GE54570
GE689486
GE86765
GO:0000166
GO:0001523
GO:0003151
GO:0003824
GO:0004745
GO:0005783
GO:0005789
GO:0005811
GO:0005886
GO:0005929
GO:0006091
GO:0006629
GO:0007601
GO:0009055
GO:0016020
GO:0016491
GO:0022900
GO:0023052
GO:0030278
GO:0042572
GO:0042622
GO:0043226
GO:0048385
GO:0048387
GO:0048856
GO:0050877
GO:0052650
GO:0060021
GO:0060349
GO:0060411
HMNXSV003025533
HMNXSV003049767
ILMN_1752478
PH_hs_0001558
PH_hs_0007279
TC01005268.hg
g4759083_3p_at
Participates
as a member of
RDH11,14,DHRS3,DHRS4 [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
DHRS3 [photoreceptor outer segment membrane]
Inferred To
Ldsdh1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
dhrs3 [endoplasmic reticulum membrane]
(Xenopus tropicalis)
dhs-3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
DHRS3 [endoplasmic reticulum membrane]
(Bos taurus)
DHRS3 [endoplasmic reticulum membrane]
(Canis familiaris)
DHRS3 [endoplasmic reticulum membrane]
(Gallus gallus)
DHRS3 [endoplasmic reticulum membrane]
(Mus musculus)
DHRS3 [endoplasmic reticulum membrane]
(Rattus norvegicus)
DHRS3 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
DHRS3 [endoplasmic reticulum membrane]
(Sus scrofa)
dhs-4 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
dhs-29 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Dmel\CG9265 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Dmel\CG15629 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
dhrs3b [endoplasmic reticulum membrane]
(Danio rerio)
dhs-19 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of DHRS3 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of DHRS3 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Homologues of DHRS3 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
firl [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_004744.2
OpenTargets
ENSG00000162496
IntEnz
1.1.1.300
GeneCards
O75911
HPA
ENSG00000162496-DHRS3
Ensembl
ENSG00000162496
,
ENSP00000480439
,
ENST00000616661
PRO
O75911
Pharos - Targets
O75911
HMDB Protein
HMDBP08892
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13503 MED21
1
MED21 [nucleoplasm]
(R-HSA-212456)
0.527
3
UniProt:Q9P296 C5AR2
1
C5AR2 [plasma membrane]
(R-HSA-964798)
0.527
2
UniProt:O60602 TLR5
1
TLR5 [plasma membrane]
(R-HSA-168013)
0.527
2
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