Reactome | MED21 [nucleoplasm]

MED21 [nucleoplasm]

Stable Identifier

R-HSA-212456

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13503 MED21

Gene Names

MED21, SRB7, SURB7

Chain

chain:1-144

Reference Genes

BioGPS Gene:9412 MED21

COSMIC (genes):MED21 MED21

CTD Gene:9412 MED21

dbSNP Gene:9412 MED21

ENSEMBL:ENSG00000152944 MED21

ENSEMBL:ENSG00000152944.9 MED21

HGNC:11473 MED21

KEGG Gene (Homo sapiens):9412 MED21

Monarch:9412 MED21

NCBI Gene:9412 MED21

OMIM:603800 MED21

UCSC:Q13503 MED21

Reference Transcript

RefSeq:NM_004264.4 MED21

Other Identifiers

11719677_a_at

11719678_a_at

11758234_s_at

11758813_x_at

16749382

209362_PM_at

209362_at

209363_PM_s_at

209363_s_at

3409007

3409008

3409012

3409013

3409014

3409015

3409016

3409017

3409018

3409019

3409020

3409021

34356_at

34357_g_at

7954503

9412

A_14_P201329

A_23_P2262

A_33_P3400547

GE61821

GE880972

GO:0000151

GO:0001824

GO:0003712

GO:0003713

GO:0003824

GO:0003899

GO:0005515

GO:0005634

GO:0006351

GO:0006355

GO:0006357

GO:0016567

GO:0016592

GO:0016740

GO:0032968

GO:0035019

GO:0036211

GO:0043226

GO:0045944

GO:0048856

GO:0051123

GO:0060261

GO:0061630

GO:0065003

GO:0070847

GO:0140096

GO:0140098

GO:0140110

HMNXSV003010953

Hs.286145.0.A2_3p_at

ILMN_1773886

PH_hs_0014800

PH_hs_0019734

TC12000262.hg

U52960_at

g1197662_3p_a_at

Participates

as a component of

Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_004255.2

OpenTargets

ENSG00000152944

GeneCards

Q13503

HPA

ENSG00000152944-MED21

Ensembl

ENSP00000282892, ENSG00000152944, ENST00000282892

PRO

Q13503

Pharos - Targets

Q13503

PDB

7ENA, 7ENJ, 7LBM, 7EMF, 8GXS, 8GXQ, 7ENC, 7NVR

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.825	6
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.802	8
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.788	8
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.763	5
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.718	6
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.669	3
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.669	3
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.643	3
UniProt:Q6ZMU5 TRIM72	1	TRIM72 [cytoplasmic vesicle membrane] (R-HSA-5263653)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3
UniProt:Q9UL45 BLOC1S6	1	BLOC1S6 [cytosol] (R-HSA-429816)	0.556	3
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.527	2
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.527	2
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.527	2
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.527	2
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.527	2
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.527	2
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.527	2
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.527	2
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.483	2

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