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ATG101 [cytosol]
Stable Identifier
R-HSA-5333634
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Autophagy-related protein 101, ATGA1_HUMAN
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
AMPK (complex) phosphorylates ULK1 (complex) (Homo sapiens)
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
Active MTORC1 binds the ULK1 complex (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
MTORC1 dissociates from ULK complex (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
Thr-180 of ULK1 is phosphorylated (Homo sapiens)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
ULK complex translocates to the ER (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
ULK1 is dephosphorylated (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK:AMP binds the ULK complex (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
MTORC1 with p-S722,S792-RPTOR:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ATG101 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BSB4 ATG101
Gene Names
ATG101, C12orf44, PP894
Chain
chain:1-218
Reference Genes
BioGPS Gene:60673 ATG101
COSMIC (genes):ATG101 ATG101
CTD Gene:60673 ATG101
dbSNP Gene:60673 ATG101
ENSEMBL:ENSG00000123395 ATG101
HGNC:25679 ATG101
KEGG:hsa:60673 ATG101
Monarch:60673 ATG101
NCBI Gene:60673 ATG101
OMIM:615089 ATG101
UCSC:Q9BSB4 ATG101
Reference Transcript
RefSeq:NM_021934.4 ATG101
RefSeq:NM_001098673.1 ATG101
Other Identifiers
11726275_a_at
16751464
218214_PM_at
218214_at
3415274
3415275
3415276
3415277
3415278
3415279
3415280
3415281
3415282
3415283
3415284
3415285
3415286
58945_f_at
60673
63295_at
7955606
A_14_P115396
A_23_P116840
GE62263
GO:0000045
GO:0000407
GO:0005515
GO:0005737
GO:0005789
GO:0005829
GO:0006914
GO:0008285
GO:0010508
GO:0019901
GO:0042802
GO:0044877
GO:1903059
GO:1990316
HMNXSV003055068
ILMN_1772527
PH_hs_0001025
TC12000415.hg
g11345473_3p_at
Participates
as a component of
p-S758-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
Other forms of this molecule
ATG101 [endoplasmic reticulum membrane]
Inferred To
Atg101 [cytosol]
(Drosophila melanogaster)
Atg101 [cytosol]
(Mus musculus)
Atg101 [cytosol]
(Rattus norvegicus)
epg-9 [cytosol]
(Caenorhabditis elegans)
atg101 [cytosol]
(Danio rerio)
atg101 [cytosol]
(Schizosaccharomyces pombe)
atg101 [cytosol]
(Xenopus tropicalis)
ATG101 [cytosol]
(Bos taurus)
ATG101 [cytosol]
(Canis familiaris)
ATG101 [cytosol]
(Dictyostelium discoideum)
ATG101 [cytosol]
(Gallus gallus)
ATG101 [cytosol]
(Sus scrofa)
Ghost homologue of ATG101 [cytosol]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_068753.2
,
NP_001092143.1
ENSEMBL
ENST00000336854
,
ENSP00000338990
OpenTargets
ENSG00000123395
HPA
ENSG00000123395-ATG101
PRO
Q9BSB4
Pharos - Targets
Q9BSB4
PDB
5XV1
,
8DO8
,
5XUY
,
5C50
,
5XV6
,
4WZG
,
5XV4
,
5XV3
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75385 ULK1
7
ULK1 [cytosol]
(R-HSA-1632847)
ULK1 [mitochondrial outer membrane]
(R-HSA-8948145)
p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
(R-HSA-8948047)
p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]
(R-HSA-5675858)
p-S317,467,556,638,T575-ULK1 [cytosol]
(R-HSA-5673747)
p-S758-ULK1 [cytosol]
(R-HSA-5672131)
ULK1 [recycling endosome]
(R-HSA-8854761)
0.827
10
UniProt:Q9GZQ8 MAP1LC3B
3
MAP1LC3B [cytosol]
(R-HSA-5205651)
MAP1LC3B(2-121) [cytosol]
(R-HSA-5682674)
MAP1LC3B [autophagosome membrane]
(R-HSA-5683641)
0.483
2
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