Reactome | PRKCSH [endoplasmic reticulum lumen]

PRKCSH [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-532666

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Glucosidase 2 subunit beta, GLU2B_HUMAN, AGER-2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P14314 PRKCSH

Gene Names

PRKCSH, G19P1

Chain

signal peptide:1-14, chain:15-528

Reference Genes

BioGPS Gene:5589 PRKCSH

COSMIC (genes):PRKCSH PRKCSH

CTD Gene:5589 PRKCSH

dbSNP Gene:5589 PRKCSH

ENSEMBL:ENSG00000130175.10 PRKCSH

HGNC:9411 PRKCSH

KEGG Gene (Homo sapiens):5589 PRKCSH

Monarch:5589 PRKCSH

NCBI Gene:5589 PRKCSH

OMIM:177060 PRKCSH

UCSC:P14314 PRKCSH

Reference Transcript

Other Identifiers

0003520184

11744126_a_at

16858468

200707_3p_at

200707_PM_at

200707_at

214080_3p_x_at

214080_PM_x_at

214080_x_at

3821201

3821202

3821203

3821204

3821205

3821206

3821208

3821210

3821211

3821214

3821215

3821216

3821219

3821220

3821221

3821223

3821224

3821225

3821226

3821228

3821230

3821232

3821234

3821236

3821243

39711_at

5589

8025895

A_14_P131637

A_14_P132080

A_24_P396197

GO:0001889

GO:0005080

GO:0005509

GO:0005515

GO:0005622

GO:0005737

GO:0005783

GO:0005788

GO:0006491

GO:0017177

GO:0023052

GO:0032991

GO:0035556

GO:0043226

GO:0043231

GO:0044325

GO:0046872

GO:0048856

GO:0051219

GO:1901135

HMNXSV003012834

Hs.1432.1.S1_3p_a_at

ILMN_1777794

ILMN_2400512

PH_hs_0040672

TC19000199.hg

TC19001981.hg

U50327_s_at

g4506076_3p_a_at

g4506076_3p_x_at

Participates

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

as a component of

glucosidase II [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

PRKCSH [plasma membrane]

p-PRKCSH [endoplasmic reticulum lumen]

Inferred To

Prkcsh [endoplasmic reticulum lumen] (Rattus norvegicus)

GCS2beta [endoplasmic reticulum lumen] (Drosophila melanogaster)

PRKCSH [endoplasmic reticulum lumen] (Bos taurus)

PRKCSH [endoplasmic reticulum lumen] (Caenorhabditis elegans)

PRKCSH [endoplasmic reticulum lumen] (Canis familiaris)

PRKCSH [endoplasmic reticulum lumen] (Danio rerio)

PRKCSH [endoplasmic reticulum lumen] (Mus musculus)

PRKCSH [endoplasmic reticulum lumen] (Sus scrofa)

Cross References

RefSeq

NP_001001329.1, NP_002734.2, XP_011526434.1, XP_016882466.1, NP_001276031.1, XP_011526433.1

OpenTargets

ENSG00000130175

HPA

ENSG00000130175-PRKCSH

GeneCards

P14314

Ensembl

ENSP00000465489, ENSG00000130175, ENST00000589838, ENST00000587327, ENST00000591462, ENSP00000465461, ENSP00000466012

PRO

P14314

Pharos - Targets

P14314

Orphanet

15141

HMDB Protein

HMDBP01163

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) Surface protein gp120 [viral envelope] (R-HIV-171211) ENV [viral envelope] (R-HIV-173439)	0.462	4