Ubiquitinated AXIN is degraded by the proteasome

Stable Identifier
R-HSA-4641256
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Ubiquitinated AXIN is degraded by the proteasome
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After ubiquitination by SMURF2, AXIN is degraded by the proteasome.

Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

endopeptidase activity of 26S proteasome [cytosol]

Physical Entity
26S proteasome [cytosol] (Homo sapiens)
Activity
endopeptidase activity (GO:0004175)
Orthologous Events
Ubiquitinated AXIN is degraded by the proteasome (Bos taurus)
Ubiquitinated AXIN is degraded by the proteasome (Canis familiaris)
Ubiquitinated AXIN is degraded by the proteasome (Danio rerio)
Ubiquitinated AXIN is degraded by the proteasome (Drosophila melanogaster)
Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)
Ubiquitinated AXIN is degraded by the proteasome (Rattus norvegicus)
Ubiquitinated AXIN is degraded by the proteasome (Sus scrofa)
Authored
Rothfels, K  (2013-09-23)
Reviewed
Rajakulendran, N  (2014-01-22)
van Amerongen, R  (2014-02-15)
Kikuchi, A  (2014-04-22)
Created
Rothfels, K  (2013-09-28)
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