Activation of Ca-permeable Kainate receptors

Stable Identifier
R-HSA-451311
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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Kainate receptors that are assembled with subunits GRIK1-5, are Ca2+ permeable if GRIK1 and GRIK2 are not edited at the Q/R or other sites.
These channels permit Ca2+ upon activation by glutamate or other agonists.

Literature References
PubMed ID Title Journal Year
8782898 Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors

Carver, JM, Mansson, PE, Cortes-Burgos, L, Shu, J, Zhou, LM, Howe, JR, Giordano, T

Brain Res 1996
9625352 Functional AMPA/kainate receptors in human embryonic and foetal central nervous system

Bardoul, M, Levallois, C, K├Ânig, N

J Chem Neuroanat 1998
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ligand-gated ion channel activity of Kainate receptor-glutamate complex [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created