Reactome | CCL2 [extracellular region]

CCL2 [extracellular region]

Stable Identifier

R-HSA-443967

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

C-C motif chemokine 2, CCL2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P13500 CCL2

Gene Names

CCL2, MCP1, SCYA2

Chain

signal peptide:1-23, chain:24-99

Reference Genes

BioGPS Gene:6347 CCL2

COSMIC (genes):CCL2 CCL2

CTD Gene:6347 CCL2

dbSNP Gene:6347 CCL2

ENSEMBL:ENSG00000108691 CCL2

HGNC:10618 CCL2

KEGG:hsa:6347 CCL2

Monarch:6347 CCL2

NCBI Gene:6347 CCL2

UCSC:P13500 CCL2

Reference Transcript

RefSeq:NM_002982.3 CCL2

Other Identifiers

11716384_at

16833204

216598_3p_s_at

216598_PM_s_at

216598_s_at

34375_at

3718169

3718170

3718171

3718172

3718173

3718174

3718175

3718176

6347

8006433

874_at

875_g_at

A_14_P125482

A_23_P89431

GO:0001525

GO:0002376

GO:0002548

GO:0003824

GO:0004672

GO:0005102

GO:0005125

GO:0005515

GO:0005576

GO:0005615

GO:0006468

GO:0006935

GO:0006954

GO:0006955

GO:0006959

GO:0007010

GO:0007155

GO:0007165

GO:0007166

GO:0007186

GO:0007187

GO:0007259

GO:0008009

GO:0008360

GO:0009617

GO:0009887

GO:0016740

GO:0019079

GO:0019221

GO:0019233

GO:0019725

GO:0030335

GO:0031727

GO:0034351

GO:0035684

GO:0043524

GO:0043615

GO:0044344

GO:0048018

GO:0048020

GO:0048245

GO:0048246

GO:0048870

GO:0050870

GO:0050877

GO:0051770

GO:0051968

GO:0060326

GO:0061844

GO:0070098

GO:0071222

GO:0071346

GO:0071347

GO:0071356

GO:0090280

GO:0098542

GO:0098772

GO:0140096

GO:1904783

GO:1905563

GO:2000134

GO:2000353

GO:2000427

GO:2000502

HMNXSV003002719

Hs.303649.1.S1_3p_a_at

Hs.303649.1.S1_3p_s_at

Hs.303649.1.S1_3p_x_at

ILMN_1720048

M26683_at

PH_hs_0015664

PH_hs_0035772

TC17000383.hg

Participates

as a member of

as an output of

Inferred To

CCL2 [extracellular region] (Bos taurus)

CCL2 [extracellular region] (Gallus gallus)

CCL2 [extracellular region] (Sus scrofa)

CCL26 [extracellular region] (Gallus gallus)

CCLi7 [extracellular region] (Gallus gallus)

CCLi8 [extracellular region] (Gallus gallus)

CCL4 [extracellular region] (Gallus gallus)

CX3CL1 [extracellular region] (Gallus gallus)

Ccl12 [extracellular region] (Mus musculus)

Ccl12 [extracellular region] (Rattus norvegicus)

CCLi9 [extracellular region] (Gallus gallus)

Homologues of CCL2 [extracellular region] (Gallus gallus)

Cross References

ZINC - World Drugs

CCL2_HUMAN

ENSEMBL

ENSP00000225831, ENST00000225831

OpenTargets

ENSG00000108691

HPA

ENSG00000108691-CCL2

ZINC - Substances

CCL2_HUMAN

ZINC target

P13500

PRO

P13500

Pharos - Targets

P13500

GlyGen

P13500

ZINC - Predictions - Purchasable

CCL2_HUMAN

HMDB Protein

HMDBP01869

PDB

1DOM, 7XA3, 1DOL, 1DON, 2NZ1, 1ML0, 2BDN, 7SO0, 1DOK, 4DN4, 8FJ0, 3IFD, 4ZK9, 4R8I

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q2F862 Q2F862			0.678	5
UniProt:P02776 PF4	4	PF4(32-101) [extracellular region] (R-HSA-61823) PF4(32-101) [platelet alpha granule lumen] (R-HSA-114652) PF4(48-101) [platelet alpha granule lumen] (R-HSA-114628) PF4(48-101) [extracellular region] (R-HSA-114629)	0.558	2
UniProt:P13501 CCL5	1	CCL5(24-91) [extracellular region] (R-HSA-373108)	0.558	2
IntAct:EBI-23184686 CCSB ORF ID			0.556	3
UniProt:P78317 RNF4	2	RNF4 [nucleoplasm] (R-HSA-5684076) RNF4 [cytosol] (R-HSA-975974)	0.556	3
UniProt:Q9Y320 TMX2			0.556	3

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