Reactome | SLC39A10 [plasma membrane]

SLC39A10 [plasma membrane]

Stable Identifier

R-HSA-442377

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

hZIP10, Zinc transporter ZIP10, S39AA_HUMAN

Locations in the PathwayBrowser

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Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
    - Metal ion SLC transporters (Homo sapiens)
      - Zinc transporters (Homo sapiens)
        
        Zinc influx into cells by the SLC39 gene family (Homo sapiens)
        
        hZIP10 mediates zinc influx into cells (Homo sapiens)
        
        SLC39A10 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9ULF5 SLC39A10

Gene Names

SLC39A10, KIAA1265, ZIP10

Chain

signal peptide:1-25, chain:26-831

Reference Genes

BioGPS Gene:57181 SLC39A10

COSMIC (genes):SLC39A10 SLC39A10

CTD Gene:57181 SLC39A10

dbSNP Gene:57181 SLC39A10

ENSEMBL:ENSG00000196950 SLC39A10

HGNC:20861 SLC39A10

KEGG:hsa:57181 SLC39A10

Monarch:57181 SLC39A10

NCBI Gene:57181 SLC39A10

OMIM:608733 SLC39A10

UCSC:Q9ULF5 SLC39A10

Reference Transcript

Other Identifiers

11720391_a_at

11733136_a_at

11747988_a_at

16889026

225295_PM_at

225295_at

2521052

2521071

2521072

2521073

2521074

2521076

2521086

2521087

2521088

2521090

2521091

2521092

2521093

2521095

2521098

2521099

2521107

2521109

2521110

2521111

50402_at

57181

8047174

A_23_P119778

GE53857

GO:0001837

GO:0002903

GO:0005215

GO:0005385

GO:0005515

GO:0005886

GO:0006829

GO:0006882

GO:0015701

GO:0016020

GO:0016324

GO:0030001

GO:0030003

GO:0030154

GO:0030890

GO:0046873

GO:0050861

GO:0055085

GO:0071577

GO:0071578

GO:0140410

HMNXSV003035286

Hs.24936.0.S1_3p_at

ILMN_1656129

PH_hs_0021941

TC02001139.hg

Cross References

Guide to Pharmacology - Targets

1189

ENSEMBL

ENSG00000196950, ENST00000409086, ENSP00000386766, ENST00000359634, ENSP00000352655

OpenTargets

ENSG00000196950

GeneCards

SLC39A10

HPA

ENSG00000196950-SLC39A10

PRO

Q9ULF5

Pharos - Targets

Q9ULF5

GlyGen

Q9ULF5

HMDB Protein

HMDBP11943

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43291 SPINT2	1	SPINT2 [extracellular region] (R-HSA-6800233)	0.527	2
UniProt:P06028 GYPB	1	GYPB [plasma membrane] (R-HSA-8867209)	0.527	2
UniProt:Q8N7X8 SIGL1			0.527	2
UniProt:Q8NCL4 GALNT6	1	GALNT6 [Golgi membrane] (R-HSA-913608)	0.527	2
UniProt:Q6ZMH5 SLC39A5	1	SLC39A5 [plasma membrane] (R-HSA-442360)	0.527	2

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