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AP3S1 [Golgi membrane]
Stable Identifier
R-HSA-434343
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
AP-3 complex subunit sigma-1, AP3S1_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3S1 [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3S1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3S1 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3S1 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
Golgi-associated Vesicle Destined Cargo [Golgi membrane] (Homo sapiens)
AP3S1 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92572 AP3S1
Gene Names
AP3S1, CLAPS3
Chain
chain:1-193
Reference Genes
BioGPS Gene:1176 AP3S1
COSMIC (genes):AP3S1 AP3S1
CTD Gene:1176 AP3S1
dbSNP Gene:1176 AP3S1
ENSEMBL:ENSG00000177879 AP3S1
HGNC:2013 AP3S1
KEGG Gene (Homo sapiens):1176 AP3S1
Monarch:1176 AP3S1
NCBI Gene:1176 AP3S1
OMIM:601507 AP3S1
UCSC:Q92572 AP3S1
Reference Transcript
RefSeq:NM_001318090.1 AP3S1
RefSeq:NM_001318091.1 AP3S1
RefSeq:NM_001318094.1 AP3S1
RefSeq:NM_001284.3 AP3S1
RefSeq:NM_001318093.1 AP3S1
RefSeq:NM_001002924.2 AP3S1
Other Identifiers
0006860114
11742902_s_at
1176
202442_at
2455505
2824875
2824881
2824882
2824884
2824886
2824897
2824898
2824899
2824900
38074_at
8107421
A_23_P69958
GE59566
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005794
GO:0006810
GO:0006886
GO:0007165
GO:0008089
GO:0008150
GO:0008286
GO:0015031
GO:0016020
GO:0016192
GO:0030117
GO:0030119
GO:0030123
GO:0030133
GO:0030659
GO:0030705
GO:0031410
GO:0032991
GO:0043226
GO:0043231
GO:0048490
GO:1904115
ILMN_1658911
ILMN_2311761
U91932_at
g4502860_3p_at
Participant Of
hasCandidate
Golgi-associated Vesicle Destined Cargo [Golgi membrane]
Other forms of this molecule
AP3S1 [cytoplasmic vesicle membrane]
Inferred To
ap3s1 [Golgi membrane] (Dictyostelium discoideum)
aps3 [Golgi membrane] (Schizosaccharomyces pombe)
Ap3s1 [Golgi membrane] (Mus musculus)
Ap3s1 [Golgi membrane] (Rattus norvegicus)
APS3 [Golgi membrane] (Saccharomyces cerevisiae)
AP3S1 [Golgi membrane] (Canis familiaris)
AP3S1 [Golgi membrane] (Gallus gallus)
AP3S1 [Golgi membrane] (Plasmodium falciparum)
AP3S1 [Golgi membrane] (Sus scrofa)
AP3S1 [Golgi membrane] (Xenopus tropicalis)
aps-3 [Golgi membrane] (Caenorhabditis elegans)
or [Golgi membrane] (Drosophila melanogaster)
Cross References
RefSeq
NP_001002924.2
,
NP_001305023.1
,
NP_001305022.1
,
NP_001305019.1
,
NP_001305020.1
,
NP_001275.1
OpenTargets
ENSG00000177879
GeneCards
Q92572
HPA
ENSG00000177879-AP3S1
Ensembl
ENST00000316788
,
ENSP00000325369
,
ENSG00000177879
PRO
Q92572
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]
7
PI(3,5)P2 [plasma membrane]
(R-ALL-1806224)
PI(3,5)P2 [phagophore assembly site membrane]
(R-ALL-5692959)
PI(3,5)P2 [Golgi membrane]
(R-ALL-1806290)
PI(3,5)P2 [early endosome membrane]
(R-ALL-1806205)
PI(3,5)P2 [late endosome membrane]
(R-ALL-1806289)
PI(3,5)P2 [endoplasmic reticulum membrane]
(R-ALL-6809774)
PI(3,5)P2 [lysosomal membrane]
(R-ALL-5334668)
0.462
2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]
6
PI(4,5)P2 [Golgi membrane]
(R-ALL-1806165)
PI(4,5)P2 [plasma membrane]
(R-ALL-179856)
PI(4,5)P2 [endoplasmic reticulum membrane]
(R-ALL-2023856)
PI(4,5)P2 [nucleoplasm]
(R-ALL-6810412)
PI(4,5)P2 [cytoplasmic vesicle membrane]
(R-ALL-8874467)
PI(4,5)P2 [early endosome membrane]
(R-ALL-8849966)
0.462
2
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