Reactome | AP3S1 [Golgi membrane]

AP3S1 [Golgi membrane]

Stable Identifier

R-HSA-434343

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

AP-3 complex subunit sigma-1, AP3S1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q92572 AP3S1

Gene Names

AP3S1, CLAPS3

Chain

chain:1-193

Reference Genes

BioGPS Gene:1176 AP3S1

COSMIC (genes):AP3S1 AP3S1

CTD Gene:1176 AP3S1

dbSNP Gene:1176 AP3S1

ENSEMBL:ENSG00000177879 AP3S1

HGNC:2013 AP3S1

KEGG Gene (Homo sapiens):1176 AP3S1

Monarch:1176 AP3S1

NCBI Gene:1176 AP3S1

OMIM:601507 AP3S1

UCSC:Q92572 AP3S1

Reference Transcript

Other Identifiers

0006860114

11742902_s_at

1176

202442_at

2455505

2824875

2824881

2824882

2824884

2824886

2824897

2824898

2824899

2824900

38074_at

8107421

A_23_P69958

GE59566

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005794

GO:0006810

GO:0006886

GO:0007165

GO:0008089

GO:0008150

GO:0008286

GO:0015031

GO:0016020

GO:0016192

GO:0030117

GO:0030119

GO:0030123

GO:0030133

GO:0030659

GO:0030705

GO:0031410

GO:0032991

GO:0043226

GO:0043231

GO:0048490

GO:1904115

ILMN_1658911

ILMN_2311761

U91932_at

g4502860_3p_at

Participant Of

hasCandidate

Golgi-associated Vesicle Destined Cargo [Golgi membrane]

Other forms of this molecule

AP3S1 [cytoplasmic vesicle membrane]

Inferred To

ap3s1 [Golgi membrane] (Dictyostelium discoideum)

aps3 [Golgi membrane] (Schizosaccharomyces pombe)

Ap3s1 [Golgi membrane] (Mus musculus)

Ap3s1 [Golgi membrane] (Rattus norvegicus)

APS3 [Golgi membrane] (Saccharomyces cerevisiae)

AP3S1 [Golgi membrane] (Canis familiaris)

AP3S1 [Golgi membrane] (Gallus gallus)

AP3S1 [Golgi membrane] (Plasmodium falciparum)

AP3S1 [Golgi membrane] (Sus scrofa)

AP3S1 [Golgi membrane] (Xenopus tropicalis)

aps-3 [Golgi membrane] (Caenorhabditis elegans)

or [Golgi membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001002924.2, NP_001305023.1, NP_001305022.1, NP_001305019.1, NP_001305020.1, NP_001275.1

OpenTargets

ENSG00000177879

GeneCards

Q92572

HPA

ENSG00000177879-AP3S1

Ensembl

ENST00000316788, ENSP00000325369, ENSG00000177879

PRO

Q92572

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]	7	PI(3,5)P2 [plasma membrane] (R-ALL-1806224) PI(3,5)P2 [phagophore assembly site membrane] (R-ALL-5692959) PI(3,5)P2 [Golgi membrane] (R-ALL-1806290) PI(3,5)P2 [early endosome membrane] (R-ALL-1806205) PI(3,5)P2 [late endosome membrane] (R-ALL-1806289) PI(3,5)P2 [endoplasmic reticulum membrane] (R-ALL-6809774) PI(3,5)P2 [lysosomal membrane] (R-ALL-5334668)	0.462	2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]	6	PI(4,5)P2 [Golgi membrane] (R-ALL-1806165) PI(4,5)P2 [plasma membrane] (R-ALL-179856) PI(4,5)P2 [endoplasmic reticulum membrane] (R-ALL-2023856) PI(4,5)P2 [nucleoplasm] (R-ALL-6810412) PI(4,5)P2 [cytoplasmic vesicle membrane] (R-ALL-8874467) PI(4,5)P2 [early endosome membrane] (R-ALL-8849966)	0.462	2

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