Reactome | Core 2a (MUC20) [Golgi lumen]

Core 2a (MUC20) [Golgi lumen]

Stable Identifier

R-HSA-6784267

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi lumen

Synonyms

Core 2 (MUC20), MUC20, MUC20_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N307 MUC20

Gene Names

MUC20, KIAA1359, UNQ2782/PRO7170

Chain

signal peptide:1-25, chain:26-709

Reference Genes

BioGPS Gene:200958 MUC20

COSMIC (genes):MUC20 MUC20

CTD Gene:200958 MUC20

dbSNP Gene:200958 MUC20

ENSEMBL:ENSG00000176945 MUC20

HGNC:23282 MUC20

KEGG:hsa:200958 MUC20

Monarch:200958 MUC20

NCBI Gene:200958 MUC20

OMIM:610360 MUC20

UCSC:Q8N307 MUC20

Reference Transcript

Other Identifiers

11727919_a_at

11739397_a_at

11758003_s_at

16949839

200958

230043_PM_at

230043_at

231941_PM_s_at

231941_s_at

243774_PM_at

243774_at

2659127

2659128

2659131

2659132

2659133

2659134

2659135

2659137

2659138

2659139

2659140

2659141

2659142

2659144

2659145

2659147

2659149

2659154

2659155

2659156

2659157

2659158

2659159

4052743

4052744

4052745

67709_at

8084895

81498_at

A_14_P135016

A_23_P92222

A_23_P92225

A_33_P3226775

GE53928

GO:0005576

GO:0005796

GO:0005886

GO:0009925

GO:0016323

GO:0016324

GO:0031528

GO:0042802

GO:0042995

GO:0048012

HMNXSV003019607

HMNXSV003027676

Hs.120845.0.A1_3p_at

Hs.299416.0.A1_3p_at

Hs.69321.0.A1_3p_x_at

ILMN_1653278

PH_hs_0004098

TC03003365.hg

p12197

p12198

p33558

p33559

Participates

as a member of

Core 2a mucins [Golgi lumen] (Homo sapiens)

Other forms of this molecule

MUC20 [plasma membrane]

GalNAc-MUC20 [plasma membrane]

Core 2 (MUC20) [Golgi lumen]

GalNAc-MUC20 [Golgi lumen]

Sialyl Tn antigen (MUC20) [Golgi lumen]

T-antigen (MUC20) [Golgi lumen]

Sialyl-2,3 T-antigen (MUC20) [Golgi lumen]

Sialyl T-antigen (MUC20) [Golgi lumen]

Disialyl T-antigen (MUC20) [Golgi lumen]

MUC20 [Golgi lumen]

Core 6 (MUC20) [Golgi lumen]

extended Core 6 (MUC20) [Golgi lumen]

Core 7 (MUC20) [Golgi lumen]

Core 3 (MUC20) [Golgi lumen]

Core 4 (MUC20) [Golgi lumen]

Core 5 (MUC20) [Golgi lumen]

Core 2S (MUC20) [Golgi lumen]

Core 8 (MUC20) [Golgi lumen]

Inferred To

Muc20 [Golgi lumen] (Mus musculus)

Muc20 [Golgi lumen] (Rattus norvegicus)

MUC20 [Golgi lumen] (Bos taurus)

MUC20 [Golgi lumen] (Canis familiaris)

MUC20 [Golgi lumen] (Sus scrofa)

Modified Residues

Name

O-(N-acetylamino)galactosyl-L-serine (N-acetyl-beta-D-glucosaminyl-(1->6)-(N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-galactosyl-(1->3))-N-acetyl-alpha-D-galactosaminyl group) at unknown position

Modification

N-acetyl-beta-D-glucosaminyl-(1->6)-(N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-galactosyl-(1->3))-N-acetyl-alpha-D-galactosaminyl group

PsiMod Name

O-(N-acetylamino)galactosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.

Cross References

RefSeq

NP_065841.1, NP_689886.3, NP_001278762.1, NP_001269435.1

OpenTargets

ENSG00000176945

ENSEMBL

ENSP00000479182, ENST00000620530, ENST00000627739, ENST00000630334, ENST00000615394, ENSP00000414350, ENSP00000479947, ENSP00000405629, ENSP00000485921, ENSP00000485837, ENSP00000485855, ENST00000610415, ENSP00000483878, ENST00000447234, ENST00000445522, ENST00000625274

HPA

ENSG00000176945-MUC20

PRO

Q8N307

Pharos - Targets

Q8N307

GlyGen

Q8N307

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BPY3 F118B			0.527	2
UniProt:P49411 TUFM	2	TUFM [mitochondrial matrix] (R-HSA-5389846) TUFM [mitochondrial outer membrane] (R-HSA-9754777)	0.527	2
UniProt:Q8IYL2 TRMT44	1	TRMT44 [cytosol] (R-HSA-6788685)	0.527	2
UniProt:Q9HD47 RANGRF	1	RANGRF [cytosol] (R-HSA-5216063)	0.527	2
UniProt:P62330 ARF6	2	ARF6 [recycling endosome membrane] (R-HSA-2029049) ARF6 [cytosol] (R-HSA-8871121)	0.527	2
UniProt:P68366 TUBA4A	9	TUBA4A [cytosol] (R-HSA-191694) TUBA4A [axonemal microtubule] (R-HSA-5610443) TUBA4A [extracellular region] (R-HSA-350734) Polyglutamyl-TUBA4A [cytosol] (R-HSA-8867386) L-isoglutamyl polyglycyl-TUBA4A [cytosol] (R-HSA-8867378) TUBA4A unfolded [cytosol] (R-HSA-392771) TUBA4A folding intermediate [cytosol] (R-HSA-392800) Ac K40 TUBA4A [axonemal microtubule] (R-HSA-5624859) AcK-TUBA4A [cytosol] (R-HSA-5618318)	0.527	2
UniProt:Q9H4B7 TUBB1	6	TUBB1 folding intermediate [cytosol] (R-HSA-392793) TUBB1 unfolded [cytosol] (R-HSA-392782) Polyglycyl-TUBB1 [cytosol] (R-HSA-8867450) Polyglutamyl-TUBB1 [cytosol] (R-HSA-8867413) TUBB1 [axonemal microtubule] (R-HSA-5610437) TUBB1 [cytosol] (R-HSA-191703)	0.527	2
UniProt:O75879 GATB			0.527	2
UniProt:Q14CZ7 FAKD3			0.527	2
UniProt:Q13509 TUBB3	6	TUBB3 [cytosol] (R-HSA-190532) TUBB3 [axonemal microtubule] (R-HSA-5610436) Polyglutamyl-TUBB3 [cytosol] (R-HSA-8867464) Polyglycyl-TUBB3 [cytosol] (R-HSA-8867372) TUBB3 unfolded [cytosol] (R-HSA-392770) TUBB3 folding intermediate [cytosol] (R-HSA-392806)	0.527	2
UniProt:Q92572 AP3S1	2	AP3S1 [Golgi membrane] (R-HSA-434343) AP3S1 [cytoplasmic vesicle membrane] (R-HSA-434205)	0.527	2

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