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CERS5 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-428168
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
LASS5, LAG1 homolog, ceramide synthase 5
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Sphingolipid de novo biosynthesis (Homo sapiens)
sphinganine + stearyl-CoA => dihydroceramide + CoASH (Homo sapiens)
LASS proteins [endoplasmic reticulum membrane] (Homo sapiens)
CERS5 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N5B7 CERS5
Gene Names
CERS5, LASS5
Chain
chain:1-392
Reference Genes
BioGPS Gene:91012 CERS5
COSMIC (genes):CERS5 CERS5
CTD Gene:91012 CERS5
dbSNP Gene:91012 CERS5
ENSEMBL:ENSG00000139624 CERS5
ENSEMBL:ENSG00000139624.14 CERS5
HGNC:23749 CERS5
KEGG Gene (Homo sapiens):91012 CERS5
Monarch:91012 CERS5
NCBI Gene:91012 CERS5
OMIM:615335 CERS5
UCSC:Q8N5B7 CERS5
Reference Transcript
RefSeq:NM_147190.3 CERS5
RefSeq:NM_001281731.1 CERS5
Other Identifiers
11730217_a_at
11730218_s_at
11747619_a_at
224951_PM_at
224951_at
3454295
3454297
3454298
3454299
3454300
3454306
3454309
3454311
3454312
3454313
3454314
3454318
3454320
3454323
3454329
3454330
53053_at
7963174
91012
A_23_P76515
A_33_P3285038
GE87172
GO:0003677
GO:0003824
GO:0005783
GO:0005789
GO:0006629
GO:0006665
GO:0014003
GO:0016020
GO:0016740
GO:0030148
GO:0030154
GO:0043226
GO:0046513
GO:0048856
GO:0050291
HMNXSV003007898
HMNXSV003011722
Hs.5331.0.S1_3p_at
ILMN_2208495
PH_hs_0026386
TC12001490.hg
Participates
as a member of
LASS proteins [endoplasmic reticulum membrane] (Homo sapiens)
Inferred To
crsA [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
lac1 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
CERS5 [endoplasmic reticulum membrane]
(Bos taurus)
CERS5 [endoplasmic reticulum membrane]
(Canis familiaris)
CERS5 [endoplasmic reticulum membrane]
(Danio rerio)
CERS5 [endoplasmic reticulum membrane]
(Gallus gallus)
CERS5 [endoplasmic reticulum membrane]
(Plasmodium falciparum)
CERS5 [endoplasmic reticulum membrane]
(Sus scrofa)
LAG1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
schlank [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Cers5 [endoplasmic reticulum membrane]
(Mus musculus)
Cers5 [endoplasmic reticulum membrane]
(Rattus norvegicus)
Homologues of CERS5 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of CERS5 [endoplasmic reticulum membrane]
(Plasmodium falciparum)
Homologues of CERS5 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
Homologues of CERS5 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
hyl-2 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
hyl-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
LAC1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
lag1 [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001268660.1
,
NP_671723.1
Guide to Pharmacology - Targets
2478
OpenTargets
ENSG00000139624
IntEnz
2.3.1.291
HPA
ENSG00000139624-CERS5
GeneCards
Q8N5B7
Ensembl
ENSP00000389050
,
ENSP00000325485
,
ENST00000317551
,
ENST00000422340
,
ENSG00000139624
PRO
Q8N5B7
Pharos - Targets
Q8N5B7
Orphanet
29619
HMDB Protein
HMDBP10978
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