ATP2B1-4 transport cytosolic Ca2+ to extracellular region

Stable Identifier
R-HSA-418309
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
PMCA extrusion of Ca2+
ReviewStatus
5/5
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The plasma membrane Ca-ATPases 1-4 (ATP2B1-4, PMCAs) are P-type Ca2+-ATPases regulated by calmodulin. The PMCA also counter-transports a proton. PMCA is important for Ca2+ homeostasis and function.
Literature References
PubMed ID Title Journal Year
5961668 ATP-dependent Ca++-extrusion from human red cells

Schatzmann, HJ

Experientia 1966
2844759 Complete primary structure of a human plasma membrane Ca2+ pump

Strehler, EE, Heim, R, Verma, AK, Filoteo, AG, Mathews, S, Fischer, R, Stanford, DR, Vogel, G, Penniston, JT, Wieben, ED

J Biol Chem 1988
Participants
Participates
Catalyst Activity

P-type calcium transporter activity of ATP2B1-4 [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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