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P2RY10 [plasma membrane]
Stable Identifier
R-HSA-418021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Putative P2Y purinoceptor 10, P2Y10_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Nucleotide-like (purinergic) receptors (Homo sapiens)
P2Y receptors (Homo sapiens)
P2Y10 receptor can bind to LPA (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00398 P2RY10
Gene Names
P2RY10
Chain
chain:1-339
Reference Genes
BioGPS Gene:27334 P2RY10
COSMIC (genes):P2RY10 P2RY10
CTD Gene:27334 P2RY10
dbSNP Gene:27334 P2RY10
ENSEMBL:ENSG00000078589.13 P2RY10
HGNC:19906 P2RY10
KEGG Gene (Homo sapiens):27334 P2RY10
Monarch:27334 P2RY10
NCBI Gene:27334 P2RY10
OMIM:300529 P2RY10
UCSC:O00398 P2RY10
Reference Transcript
RefSeq:NM_001324218.1 P2RY10
RefSeq:NM_014499.3 P2RY10
RefSeq:NM_198333.2 P2RY10
Other Identifiers
0005420519
0006650039
11741190_a_at
1553856_PM_s_at
1553856_s_at
17105076
214615_PM_at
214615_at
236280_PM_at
236280_at
27334
358_at
36413_at
3982563
3982564
3982566
3982568
3982571
3982572
3982573
3982575
3982577
8168524
83391_at
AF000545_at
A_14_P113024
A_23_P217187
A_23_P346376
GE54021
GE835711
GO:0004930
GO:0005886
GO:0005887
GO:0007165
GO:0007186
GO:0016020
GO:0016021
GO:0023052
GO:0035025
GO:0035589
GO:0045028
GO:0051482
GO:0055065
GO:0060089
HMNXSV003054113
Hs.176920.0.A1_3p_at
Hs2.396782.1.S1_3p_s_at
ILMN_1784774
ILMN_2321578
PH_hs_0015335
PH_hs_0030654
TC0X000427.hg
Participates
as an input of
P2Y10 receptor can bind to LPA (Homo sapiens)
as a member of
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
as a component of
P2RY10:LPA [plasma membrane] (Homo sapiens)
Inferred To
LOC422147 [plasma membrane]
(Gallus gallus)
P2RY10 [plasma membrane]
(Bos taurus)
P2RY10 [plasma membrane]
(Canis familiaris)
P2RY10 [plasma membrane]
(Danio rerio)
P2RY10 [plasma membrane]
(Gallus gallus)
P2RY10 [plasma membrane]
(Sus scrofa)
Homologues of P2RY10 [plasma membrane]
(Gallus gallus)
gnrr-4 [plasma membrane]
(Caenorhabditis elegans)
p2ry10 [plasma membrane]
(Xenopus tropicalis)
P2ry10 [plasma membrane]
(Mus musculus)
P2ry10 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_055314.1
,
NP_001311147.1
,
NP_938147.1
Guide to Pharmacology - Targets
165
OpenTargets
ENSG00000078589
GeneCards
O00398
HPA
ENSG00000078589-P2RY10
Ensembl
ENST00000171757
,
ENST00000544091
,
ENSG00000078589
,
ENSP00000171757
,
ENSP00000443138
PRO
O00398
Pharos - Targets
O00398
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