Reactome | FOXC1 [nucleoplasm]

FOXC1 [nucleoplasm]

Stable Identifier

R-HSA-3927815

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Forkhead box protein C1, FOXC1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q12948 FOXC1

Gene Names

FOXC1, FKHL7, FREAC3

Chain

chain:1-553

Reference Genes

BioGPS Gene:2296 FOXC1

COSMIC (genes):FOXC1 FOXC1

CTD Gene:2296 FOXC1

dbSNP Gene:2296 FOXC1

ENSEMBL:ENSG00000054598 FOXC1

ENSEMBL_homo_sapiens_GENE:ENSG00000054598.9 FOXC1

HGNC:3800 FOXC1

KEGG Gene (Homo sapiens):2296 FOXC1

Monarch:2296 FOXC1

NCBI Gene:2296 FOXC1

OMIM:601090 FOXC1

Reference Transcript

RefSeq:NM_001453.2 FOXC1

Other Identifiers

11719778_s_at

11753509_a_at

11758111_s_at

1553613_PM_s_at

1553613_s_at

17004208

213260_PM_at

213260_at

2296

2891769

2891770

2891771

2891772

2891773

2891774

2891775

2891776

2891777

2891778

2891779

2891780

2891781

2891782

2891783

2891785

2891787

41027_at

61298_at

8116591

A_14_P115348

A_23_P390504

A_32_P205110

GE80442

GE86049

GO:0000122

GO:0000278

GO:0000785

GO:0000792

GO:0000976

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0001501

GO:0001503

GO:0001525

GO:0001541

GO:0001568

GO:0001654

GO:0001657

GO:0001701

GO:0001756

GO:0001822

GO:0001945

GO:0001958

GO:0001974

GO:0003007

GO:0003013

GO:0003275

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006351

GO:0006355

GO:0006357

GO:0007219

GO:0007420

GO:0007507

GO:0008283

GO:0008301

GO:0008354

GO:0009653

GO:0010628

GO:0010718

GO:0012501

GO:0014031

GO:0014032

GO:0016477

GO:0016525

GO:0021549

GO:0022414

GO:0023052

GO:0030154

GO:0030198

GO:0030199

GO:0030203

GO:0032808

GO:0035050

GO:0036438

GO:0038084

GO:0042475

GO:0043010

GO:0043226

GO:0043388

GO:0043565

GO:0045618

GO:0045893

GO:0045930

GO:0045944

GO:0046620

GO:0048010

GO:0048341

GO:0048513

GO:0048762

GO:0048844

GO:0048856

GO:0048870

GO:0055010

GO:0060038

GO:0061629

GO:0070098

GO:0071364

GO:0072010

GO:0097746

GO:0140110

GO:0140297

GO:1901135

GO:1901491

GO:1901534

GO:1902038

GO:1902257

GO:1904798

GO:1990841

GO:1990869

HMNXSV003040747

Hs.284186.0.A2_3p_at

Hs2.348883.1.S1_3p_s_at

ILMN_1738401

PH_hs_0016832

TC06000012.hg

TC06002402.hg

TC06002403.hg

This entity regulates

Negatively

Cross References

RefSeq

NP_001444.2

OpenTargets

ENSG00000054598

GeneCards

Q12948

HPA

ENSG00000054598-FOXC1

Ensembl

ENST00000645831, ENSP00000493906, ENSG00000054598

PRO

Q12948

Pharos - Targets

Q12948

Orphanet

16064

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40424 PBX1	1	PBX1 [nucleoplasm] (R-HSA-453045)	0.702	5
UniProt:Q66LE6 PPP2R2D	1	PPP2R2D [nucleoplasm] (R-HSA-2160962)	0.643	4
UniProt:Q07021 C1QBP	3	C1QBP [cytosol] (R-HSA-9645690) C1QBP [mitochondrial matrix] (R-HSA-9645697) C1QBP [plasma membrane] (R-HSA-158123)	0.61	6
UniProt:P21333 FLNA	3	FLNA [extracellular region] (R-HSA-350712) p-S2152-FLNA [cytosol] (R-HSA-5669246) FLNA [cytosol] (R-HSA-210019)	0.61	8
UniProt:Q9Q2G4 Q9Q2G4			0.558	3
UniProt:Q99697-3 PITX2			0.556	6
UniProt:Q8TCB7 METL6			0.527	2
UniProt:P30153 PPP2R1A	2	PPP2R1A [nucleoplasm] (R-HSA-165968) PPP2R1A [cytosol] (R-HSA-165982)	0.527	2
UniProt:P11142 HSPA8	10	Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.527	2
UniProt:P63151 PPP2R2A	2	PPP2R2A [cytosol] (R-HSA-377253) PPP2R2A [nucleoplasm] (R-HSA-1564978)	0.527	2
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.483	2
UniProt:P08651 NFIC	1	NFIC [nucleoplasm] (R-HSA-60138)	0.483	2