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SKIV2L [cytosol]
Stable Identifier
R-HSA-391294
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Skiv2l
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
mRNA decay by 3' to 5' exoribonuclease (Homo sapiens)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Homo sapiens)
Exosome:SKI complex [cytosol] (Homo sapiens)
SKI complex [cytosol] (Homo sapiens)
SKIV2L [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)
Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) (Homo sapiens)
CCT/TRiC:substrate complex [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
SKIV2L [cytosol] (Homo sapiens)
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
SKIV2L [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15477 SKIC2
Gene Names
SKIC2, DDX13, SKI2W, SKIV2, SKIV2L, W
Chain
chain:1-1246
Reference Genes
BioGPS Gene:6499 SKIC2
CTD Gene:6499 SKIC2
dbSNP Gene:6499 SKIC2
ENSEMBL:ENSG00000204351 SKIV2L
ENSEMBL_homo_sapiens_GENE:ENSG00000204351.13 SKIC2
ENSEMBL_homo_sapiens_GENE:ENSG00000206353.11 SKIC2
ENSEMBL_homo_sapiens_GENE:ENSG00000223493.9 SKIC2
ENSEMBL_homo_sapiens_GENE:ENSG00000225737.9 SKIC2
ENSEMBL_homo_sapiens_GENE:ENSG00000228896.9 SKIC2
ENSEMBL_homo_sapiens_GENE:ENSG00000232616.9 SKIC2
HGNC:10898 SKIC2
KEGG Gene (Homo sapiens):6499 SKIC2
Monarch:6499 SKIC2
NCBI Gene:6499 SKIC2
OMIM:600478 SKIC2
UCSC:Q15477 SKIC2
Reference Transcript
RefSeq:NM_006929.4 SKIC2
Other Identifiers
11746839_a_at
11753164_a_at
11760615_x_at
17006984
17028113
17030923
17035686
17038418
17040967
203727_PM_at
203727_at
2902886
2902887
2902889
2902890
2902891
2902892
2902893
2902895
2902896
2902898
2902899
2902902
2902903
2902906
2902907
2902908
2902909
2902911
2902912
2902914
2902915
2902916
2902917
2902918
2902919
2902920
2902922
2902923
2902924
2902927
2902928
2902930
2902931
2902933
2902934
37998_at
6499
8118367
8178136
8179364
A_23_P168080
GE58911
GO:0000166
GO:0003676
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006401
GO:0016071
GO:0016787
GO:0016887
GO:0034458
GO:0043226
GO:0055087
GO:0070478
GO:0072344
GO:0140098
GO:0140657
HMNXSV003019635
HMNXSV003030766
HMNXSV003047243
ILMN_1666512
PH_hs_0005025
TC06000389.hg
TC6_cox_hap2000083.hg
TC6_dbb_hap3000074.hg
TC6_mcf_hap5000066.hg
TC6_qbl_hap6000075.hg
TC6_ssto_hap7000067.hg
U09877_at
g13787218_3p_at
Participates
as a candidate of
unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)
as a component of
SKI complex [cytosol] (Homo sapiens)
Inferred To
SKIV2L [cytosol]
(Dictyostelium discoideum)
SKIV2L [cytosol]
(Gallus gallus)
SKIV2L [cytosol]
(Mus musculus)
SKIV2L [cytosol]
(Saccharomyces cerevisiae)
SKIV2L [cytosol]
(Schizosaccharomyces pombe)
skic2 [cytosol]
(Xenopus tropicalis)
SKIC2 [cytosol]
(Bos taurus)
SKIC2 [cytosol]
(Sus scrofa)
Ghost homologue of SKIV2L [cytosol]
(Canis familiaris)
Skic2 [cytosol]
(Rattus norvegicus)
tst [cytosol]
(Drosophila melanogaster)
skih-2 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_008860.4
IntEnz
3.6.4.13
GeneCards
Q15477
HPA
ENSG00000204351-SKIC2
Ensembl
ENSG00000225737
,
ENST00000375394
,
ENSP00000372827
,
ENSP00000399530
,
ENSP00000412310
,
ENSP00000394400
,
ENSP00000400626
,
ENST00000429465
,
ENST00000412823
,
ENSG00000232616
,
ENSG00000228896
,
ENSG00000206353
,
ENSG00000204351
,
ENST00000383336
,
ENSG00000223493
,
ENST00000421789
,
ENSP00000364543
,
ENST00000448219
PRO
Q15477
Pharos - Targets
Q15477
Orphanet
21094
PDB
7QE0
,
7QDZ
,
7QDY
,
7QDR
,
7QDS
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54646 PRKAA2
4
PRKAA2 [cytosol]
(R-HSA-200405)
p-T172-PRKAA2 [cytosol]
(R-HSA-200417)
p-T172-PRKAA2 [nucleoplasm]
(R-HSA-164171)
PRKAA2 [nucleoplasm]
(R-HSA-163682)
0.556
3
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