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Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
Stable Identifier
R-HSA-390339
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Regulation of T cell activation by CD28 family (Homo sapiens)
Co-inhibition by PD-1 (Homo sapiens)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Homo sapiens)
Participants
components
CD4 [plasma membrane]
(Homo sapiens)
MHC Class II bearing antigen peptide [plasma membrane]
(Homo sapiens)
p-Y394-LCK [cytosol]
(Homo sapiens)
T-cell receptor complex with dephosphorylated CD3 zeta chain [plasma membrane]
(Homo sapiens)
Participates
as an output of
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)
Inferred To
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Bos taurus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Canis familiaris)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Gallus gallus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Mus musculus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Rattus norvegicus)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane]
(Sus scrofa)
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