Reactome | PFDN6 [cytosol]

PFDN6 [cytosol]

Stable Identifier

R-HSA-379547

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O15212 PFDN6

Gene Names

PFDN6, HKE2, PFD6

Chain

initiator methionine:, chain:2-129

Reference Genes

BioGPS Gene:10471 PFDN6

COSMIC (genes):PFDN6 PFDN6

CTD Gene:10471 PFDN6

dbSNP Gene:10471 PFDN6

ENSEMBL:ENSG00000204220 PFDN6

HGNC:4926 PFDN6

Monarch:10471 PFDN6

NCBI Gene:10471 PFDN6

OMIM:605660 PFDN6

UCSC:O15212 PFDN6

Reference Transcript

Other Identifiers

10471

11727890_a_at

17007446

17028495

17031309

17036058

17038779

222019_PM_at

222019_at

222029_PM_x_at

222029_x_at

233588_PM_x_at

233588_x_at

242048_PM_at

242048_at

2903589

2903590

2903591

2903592

2903594

2903595

2903596

2903597

2903598

2903599

2903600

2903601

2903602

2903607

35963_at

55975_at

58884_at

70313_at

8118661

8178270

8179559

A_14_P125596

A_23_P122563

A_32_P175462

A_33_P3264444

GE79721

GE87546

GO:0001540

GO:0005515

GO:0005737

GO:0006457

GO:0016272

GO:0050821

GO:0051082

GO:0051087

GO:0051131

GO:0061077

GO:0065003

GO:0101031

GO:1905907

GO:1990062

HMNXSV003007926

HMNXSV003020241

HMNXSV003038191

Hs.205736.1.S1_3p_x_at

Hs.205736.2.S1_3p_a_at

Hs.205736.2.S1_3p_x_at

Hs.205736.3.A1_3p_a_at

Hs.209117.0.S1_3p_at

ILMN_1661490

PH_hs_0021938

TC06000419.hg

TC6_cox_hap2000109.hg

TC6_dbb_hap3000101.hg

TC6_mcf_hap5000094.hg

TC6_qbl_hap6000100.hg

Participates

as a component of

Prefoldin [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000204220

ENSEMBL

ENST00000374607, ENST00000547641, ENST00000442285, ENSP00000404773, ENST00000445559, ENSP00000412319, ENSP00000363738, ENSP00000363734, ENSP00000363735, ENSP00000448607, ENST00000552711, ENSP00000372694, ENST00000374606, ENSP00000395462, ENSP00000447540, ENSP00000382316, ENSP00000382314, ENST00000412289, ENST00000547952, ENSP00000398171, ENST00000383207, ENST00000548040, ENST00000451970, ENST00000431830, ENST00000448594, ENSP00000378563, ENST00000452658, ENST00000399385, ENSP00000415678, ENSP00000449925, ENST00000432391, ENST00000399383, ENSP00000403771, ENSP00000402553, ENSP00000400152, ENSP00000402212, ENST00000425878, ENSP00000448784, ENST00000374610, ENST00000395131

HPA

ENSG00000204220-PFDN6

PRO

O15212

Pharos - Targets

O15212

GlyGen

O15212

PDB

6NRC, 6NRB, 6NRD, 6NR8, 6NR9, 7WU7

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.643	3
UniProt:Q13164 MAPK7	4	p-T218,Y221-MAPK7 [nucleoplasm] (R-HSA-198738) p-T218,Y221-MAPK7 [cytosol] (R-HSA-198721) MAPK7 [cytosol] (R-HSA-198754) MAPK7 [nucleoplasm] (R-HSA-199961)	0.643	4
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.569	3
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	3
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.527	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.483	5