Reactome | EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]

Stable Identifier

R-HSA-3780999

Type

Complex

Species

Homo sapiens

Compartment

cytosol

Synonyms

laforin:PTG:phosphoglycogen-GYG1:GYS1-a tetramer

GO Cellular Component

glycogen granule (0042587)

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
25538239	Dimeric quaternary structure of human laforin Cingolani, G, Sankhala, RS, Nitschke, F, Ho, L, Minassian, BA, Koksal, AC	J. Biol. Chem.	2015
25544560	Structural mechanism of laforin function in glycogen dephosphorylation and lafora disease Parker, MW, Husodo, S, Bridges, TM, Auger, KD, Hellman, LM, Turner, BD, Li, S, Hsu, S, Gentry, MS, Meekins, DA, Chakravarthy, S, Vander Kooi, CW, Brewer, MK, Paasch, BC, Woods, VL, Sherwood, AR, Wong, BK, Taylor, AO, Dukhande, VV, Raththagala, M, Sanz, P	Mol. Cell	2015
16901901	Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates Gentry, MS, Worby, CA, Dixon, JE	J. Biol. Chem.	2006
18070875	Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG) Gentry, MS, Worby, CA, Dixon, JE	J. Biol. Chem.	2008

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