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polysaccharide-P-GYG1 [cytosol]
Stable Identifier
R-HSA-3777092
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
polysaccharide-P-glycogenin-1
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of carbohydrate metabolism (Homo sapiens)
Glycogen storage diseases (Homo sapiens)
Myoclonic epilepsy of Lafora (Homo sapiens)
Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) (Homo sapiens)
EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
mutant EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycogen metabolism (Homo sapiens)
Glycogen synthesis (Homo sapiens)
EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex (Homo sapiens)
EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Homo sapiens)
EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Homo sapiens)
PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
polysaccharide-P-GYG1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46976 GYG1
Gene Names
GYG1, GYG
Chain
initiator methionine:, chain:2-350
Reference Genes
BioGPS Gene:2992 GYG1
COSMIC (genes):GYG1 GYG1
CTD Gene:2992 GYG1
dbSNP Gene:2992 GYG1
ENSEMBL:ENSG00000163754 GYG1
ENSEMBL_homo_sapiens_GENE:ENSG00000163754.18 GYG1
HGNC:4699 GYG1
KEGG Gene (Homo sapiens):2992 GYG1
Monarch:2992 GYG1
NCBI Gene:2992 GYG1
OMIM:603942 GYG1
UCSC:P46976 GYG1
Reference Transcript
RefSeq:NM_001184720.1 GYG1
RefSeq:NM_004130.3 GYG1
RefSeq:NM_001184721.1 GYG1
Other Identifiers
11737814_a_at
11744373_s_at
11750078_a_at
16946762
201554_PM_x_at
201554_x_at
211275_PM_s_at
211275_s_at
2647155
2647157
2647158
2647159
2647167
2647170
2647171
2647173
2647175
2647176
2647178
2647180
2647182
2647184
2647186
2992
40876_at
8083272
A_23_P29422
A_23_P384517
A_32_P210798
GE59077
GO:0003824
GO:0005515
GO:0005576
GO:0005737
GO:0005764
GO:0005773
GO:0005829
GO:0005975
GO:0005978
GO:0006091
GO:0008466
GO:0016020
GO:0016740
GO:0016757
GO:0030145
GO:0031410
GO:0034774
GO:0042803
GO:0043202
GO:0043226
GO:0046872
GO:0102751
GO:1904813
HMNXSV003026950
ILMN_2230862
PH_hs_0010438
g4758491_3p_a_at
Participates
as a component of
mutant EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
EPM2A:PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
Other forms of this molecule
GYG1 T83M [cytosol]
poly((1,4)-alpha-glucosyl)GYG1 [lysosomal lumen]
glycogen-GYG1 [lysosomal lumen]
oligo((1,4)-alpha-glucosyl) GYG1 [cytosol]
GYG1 [secretory granule lumen]
GYG1 [extracellular region]
GYG1 [ficolin-1-rich granule lumen]
glycogen-GYG1 [cytosol]
limit dextrin-glycogenin-1 [cytosol]
((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)GYG1 [cytosol]
GYG1 [cytosol]
poly((1,4)-alpha-glucosyl)GYG1 [cytosol]
Inferred To
Gyg [cytosol]
(Drosophila melanogaster)
GYG1 [cytosol]
(Bos taurus)
GYG1 [cytosol]
(Canis familiaris)
GYG1 [cytosol]
(Gallus gallus)
GYG1 [cytosol]
(Sus scrofa)
gyg1b [cytosol]
(Danio rerio)
gyg1a [cytosol]
(Danio rerio)
gyg-2 [cytosol]
(Caenorhabditis elegans)
Homologues of polysaccharide-P-GYG1 [cytosol]
(Caenorhabditis elegans)
Homologues of polysaccharide-P-GYG1 [cytosol]
(Danio rerio)
Homologues of polysaccharide-P-GYG1 [cytosol]
(Saccharomyces cerevisiae)
polysaccharide-P-GYG1 [cytosol]
(Caenorhabditis elegans)
polysaccharide-P-GYG1 [cytosol]
(Mus musculus)
polysaccharide-P-GYG1 [cytosol]
(Rattus norvegicus)
polysaccharide-P-GYG1 [cytosol]
(Saccharomyces cerevisiae)
IDS2 [cytosol]
(Saccharomyces cerevisiae)
Modified Residues
Name
O4'-glucosyl-L-tyrosine (polysaccharide phosphate group) at 195
Coordinate
195
Modification
polysaccharide phosphate group
PsiMod Name
O4'-glucosyl-L-tyrosine [MOD:00166]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-glucosyl-tyrosine.
Cross References
RefSeq
NP_004121.2
,
NP_001171649.1
,
NP_001171650.1
OpenTargets
ENSG00000163754
GeneCards
P46976
HPA
ENSG00000163754-GYG1
Ensembl
ENST00000296048
,
ENST00000345003
,
ENSP00000420683
,
ENST00000484197
,
ENSG00000163754
,
ENSP00000340736
,
ENSP00000296048
PRO
P46976
Pharos - Targets
P46976
Orphanet
20269
HMDB Protein
HMDBP01093
PDB
8CVZ
,
3Q4S
,
3U2U
,
8CVY
,
6EQL
,
3RMW
,
3U2V
,
3T7O
,
8CVX
,
7Q13
,
3QVB
,
7OVX
,
3T7N
,
3RMV
,
6EQJ
,
7Q0B
,
7ZBN
,
3U2W
,
3T7M
,
3U2T
,
7Q0S
,
7Q12
,
3U2X
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