EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex

Stable Identifier
R-HSA-3781001
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
4/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
EPM2A (laforin) dimer binds to the PPP1R3C:phosphoglycogen-GYG1 (glycogenin 1) complex, probably through interactions with the PPP1R3C (PTG) and glycogen moieties of the complex (Worby et al. 2008).
Literature References
PubMed ID Title Journal Year
18070875 Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG)

Gentry, MS, Worby, CA, Dixon, JE

J. Biol. Chem. 2008
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein-macromolecule adaptor activity of PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol]

Physical Entity
PPP1R3C:phosphoglycogen-GYG1:GYS1-a tetramer [cytosol] (Homo sapiens)
Activity
protein-macromolecule adaptor activity (GO:0030674)
Authored
D'Eustachio, P  (2013-07-19)
Reviewed
Jassal, B  (2013-07-26)
Pederson, B  (2014-02-19)
Created
D'Eustachio, P  (2013-06-28)
Cite Us!