Reactome | DBC1 [nucleoplasm]

DBC1 [nucleoplasm]

Stable Identifier

R-HSA-3371479

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KIAA1967, DBIRD complex subunit KIAA1967, Deleted in breast cancer gene 1 protein, p30 DBC

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8N163 CCAR2

Gene Names

CCAR2, DBC1, KIAA1967

Chain

chain:1-923

Reference Genes

BioGPS Gene:57805 CCAR2

COSMIC (genes):CCAR2 CCAR2

CTD Gene:57805 CCAR2

dbSNP Gene:57805 CCAR2

ENSEMBL:ENSG00000158941 CCAR2

HGNC:23360 CCAR2

KEGG Gene (Homo sapiens):57805 CCAR2

Monarch:57805 CCAR2

NCBI Gene:57805 CCAR2

OMIM:607359 CCAR2

UCSC:Q8N163 CCAR2

Reference Transcript

RefSeq:NM_021174.5 CCAR2

Other Identifiers

0004120397

0006290091

11722676_a_at

11748940_a_at

17066733

225187_at

3089596

3089598

3089599

3089600

3089601

3089602

3089604

3089605

3089606

3089607

3089608

3089609

3089611

3089616

3089618

3089619

3089620

3089621

3089623

3089624

3089625

3089626

3089627

3089628

3089629

3089632

3089633

3089634

3089635

3089638

3089639

3089640

3089641

3089642

48581_at

57805

8145201

A_14_P101308

A_14_P128717

A_24_P38446

GE86972

GO:0000228

GO:0000790

GO:0000993

GO:0003674

GO:0003723

GO:0004857

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005739

GO:0005759

GO:0006355

GO:0006397

GO:0006464

GO:0006915

GO:0006950

GO:0006974

GO:0007005

GO:0007049

GO:0007165

GO:0007267

GO:0008150

GO:0008219

GO:0008380

GO:0009056

GO:0009058

GO:0009411

GO:0016055

GO:0019899

GO:0030234

GO:0030308

GO:0030374

GO:0031647

GO:0032435

GO:0032784

GO:0032991

GO:0034641

GO:0040007

GO:0042752

GO:0043065

GO:0043086

GO:0043226

GO:0043653

GO:0044609

GO:0045892

GO:0048511

GO:0090263

GO:0090311

GO:1900034

GO:1902230

GO:1903508

GO:2000003

Hs.181102.2.S1_3p_at

Hs.181102.2.S1_3p_x_at

ILMN_1699473

ILMN_1786345

ILMN_1804789

PH_hs_0033327

TC08000175.hg

TC08001835.hg

Participant Of

input

DBC1 is phosphorylated by ATM/ART

Other forms of this molecule

p-T454-DBC1 [nucleoplasm]

Inferred To

Ccar2 [nucleoplasm] (Mus musculus)

Ccar2 [nucleoplasm] (Rattus norvegicus)

CCAR2 [nucleoplasm] (Bos taurus)

CCAR2 [nucleoplasm] (Canis familiaris)

CCAR2 [nucleoplasm] (Sus scrofa)

ccar2 [nucleoplasm] (Danio rerio)

ccar-1 [nucleoplasm] (Caenorhabditis elegans)

DG1124 [nucleoplasm] (Dictyostelium discoideum)

Cross References

RefSeq

NP_066997.3

OpenTargets

ENSG00000158941

GeneCards

Q8N163

HPA

ENSG00000158941-CCAR2

Ensembl

ENSP00000373930, ENSP00000310670, ENST00000389279, ENST00000308511, ENSG00000158941

PRO

Q8N163

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.769	16
UniProt:P01106 MYC	2	PolyUb-MYC [nucleoplasm] (R-HSA-6783169) MYC [nucleoplasm] (R-HSA-188379)	0.749	9
UniProt:Q9H4Z2 ZNF335	1	ZNF335 [nucleoplasm] (R-HSA-6810129)	0.621	5
UniProt:Q15628 TRADD	1	TRADD [cytosol] (R-HSA-66376)	0.564	2
UniProt:Q96L14 C170L			0.564	2
UniProt:Q9Q2G4 Q9Q2G4			0.558	5
UniProt:P02766 TTR	2	TTR [azurophil granule lumen] (R-HSA-6799366) TTR [extracellular region] (R-HSA-976883)	0.556	3
UniProt:O76024 WFS1	3	p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q05322 VP24			0.527	3
UniProt:P03366 POL			0.462	2
UniProt:Q66LE6 PPP2R2D	1	PPP2R2D [nucleoplasm] (R-HSA-2160962)	0.462	2
UniProt:P63151 PPP2R2A	2	PPP2R2A [nucleoplasm] (R-HSA-1564978) PPP2R2A [cytosol] (R-HSA-377253)	0.462	2

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