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3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region]
Stable Identifier
R-HSA-2468118
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
4-Hyp 5-Gal-Hyl collagen alpha-1(IV) chain C-term fragment
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Collagen degradation (Homo sapiens)
Collagen type IV degradation by MMP2,3,4,9,10,12 (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
Gelatin degradation by MMP19 (Homo sapiens)
Cleaved collagen fibrils [extracellular region] (Homo sapiens)
Cleaved collagen type IV networks [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Cleaved collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens [extracellular region] (Homo sapiens)
Cleaved tropocollagen alpha-1(IV).alpha-1(IV). alpha-2(IV) [extracellular region] (Homo sapiens)
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
3x4Hyp-GalHyl-COL4A1(?-1669) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02462 COL4A1
Gene Names
COL4A1
Chain
signal peptide:1-27, propeptide:28-172, chain:173-1669, chain:1445-1669
Reference Genes
BioGPS Gene:1282 COL4A1
COSMIC (genes):COL4A1 COL4A1
CTD Gene:1282 COL4A1
dbSNP Gene:1282 COL4A1
ENSEMBL:ENSG00000187498 COL4A1
ENSEMBL_homo_sapiens_GENE:ENSG00000187498.16 COL4A1
HGNC:2202 COL4A1
KEGG Gene (Homo sapiens):1282 COL4A1
Monarch:1282 COL4A1
NCBI Gene:1282 COL4A1
OMIM:120130 COL4A1
UCSC:P02462 COL4A1
Reference Transcript
RefSeq:NM_001303110.1 COL4A1
RefSeq:NM_001845.5 COL4A1
Other Identifiers
11716638_s_at
11716639_a_at
11760558_at
1282
16780929
211980_PM_at
211980_at
211981_PM_at
211981_at
3525314
3525315
3525316
3525317
3525318
3525319
3525320
3525321
3525324
3525326
3525327
3525330
3525331
3525332
3525333
3525334
3525337
3525338
3525341
3525343
3525345
3525346
3525347
3525350
3525352
3525354
3525355
3525356
3525357
3525358
3525359
3525360
3525362
3525363
3525365
3525366
3525367
3525371
3525373
3525374
3525376
3525378
3525380
3525382
3525383
3525385
3525387
3525388
3525389
3525392
3525393
3525394
3525395
3525397
3525399
3525400
3525401
3525403
3525405
3525414
3525433
3525434
39333_at
59548_at
73188_s_at
7972750
A_23_P65240
A_24_P68342
GE635613
GE79587
GO:0001525
GO:0001569
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007420
GO:0007528
GO:0023052
GO:0030020
GO:0030154
GO:0030198
GO:0030312
GO:0030855
GO:0031012
GO:0034330
GO:0038063
GO:0043226
GO:0048407
GO:0048514
GO:0048856
GO:0061304
GO:0061333
GO:0062023
GO:0071230
GO:0071711
HMNXSV003003349
Hs.119129.0.A1_3p_at
Hs.119129.0.A2_3p_at
ILMN_1653028
M26576_cds2_at
PH_hs_0025581
TC13000872.hg
Participates
as a member of
Cleaved collagen alpha-1(IV) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
GlcGalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
GalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-GlcGalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
5Hyl-COL4A1(24-1669) [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-1(IV) chain [extracellular region]
3,4-Hyp 5-sulfiliminyl collagen alpha-1(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-1(IV) chain [extracellular region]
3x4Hyp-COL4A1(24-?) [extracellular region]
COL4A1(?-1669) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A1(?-1669) [extracellular region]
COL4A1(24-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A1(24-?) [extracellular region]
GalHyl-COL4A1(24-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A1(24-?) [extracellular region]
GlcGalHyl-COL4A1(?-1669) [extracellular region]
3x4Hyp-3Hyp-COL4A1(24-?) [extracellular region]
3x4Hyp-GalHyl-COL4A1(24-?) [extracellular region]
3x4Hyp-5Hyl-COL4A1(?-1669) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A1(24-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A1(?-1669) [extracellular region]
GlcGalHyl-COL4A1(24-?) [extracellular region]
3x4Hyp-5Hyl-COL4A1(24-?) [extracellular region]
5Hyl-COL4A1(24-?) [extracellular region]
3x4Hyp-3Hyp-COL4A1(?-1669) [extracellular region]
5Hyl-COL4A1(?-1669) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A1(?-1669) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A1(?-1669) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A1(24-?) [extracellular region]
3x4Hyp-COL4A1(?-1669) [extracellular region]
GalHyl-COL4A1(?-1669) [extracellular region]
GlcGalHyl-COL4A1(173-1669) [extracellular region]
5Hyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-3Hyp-COL4A1(173-1669) [extracellular region]
GalHyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-COL4A1(173-1669) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-5Hyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A1(173-1669) [extracellular region]
3x4Hyp-GalHyl-COL4A1(173-1669) [extracellular region]
COL4A1(1445-1669) [extracellular region]
3x4Hyp-GalHyl-COL4A1(1445-1669) [extracellular region]
COL4A1(173-1669) [extracellular region]
GlcGalHyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-5Hyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A1(1445-1669) [extracellular region]
5Hyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A1((1445-1669)) [extracellular region]
GalHyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-COL4A1(1445-1669) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A1(1445-1669) [extracellular region]
3x4Hyp-3Hyp-COL4A1(1445-1669) [extracellular region]
Inferred To
COL4A1 [extracellular region]
(Bos taurus)
COL4A1 [extracellular region]
(Canis familiaris)
COL4A1 [extracellular region]
(Gallus gallus)
COL4A1 [extracellular region]
(Sus scrofa)
col4a1 [extracellular region]
(Xenopus tropicalis)
Col4a1 [extracellular region]
(Mus musculus)
Col4a1 [extracellular region]
(Rattus norvegicus)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
O5-galactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-galactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_001290039.1
,
NP_001836.3
OpenTargets
ENSG00000187498
HPA
ENSG00000187498-COL4A1
GeneCards
P02462
Ensembl
ENST00000375820
,
ENSG00000187498
,
ENSP00000364979
,
ENST00000543140
,
ENSP00000443348
PRO
P02462
Pharos - Targets
P02462
Orphanet
15771
PDB
1LI1
,
5NAY
,
5NAX
,
6MPX
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14780 MMP9
8
MMP9 [ficolin-1-rich granule lumen]
(R-HSA-6800973)
MMP9 [tertiary granule lumen]
(R-HSA-6800181)
MMP9(60-106) [extracellular region]
(R-HSA-1604699)
MMP9(60-707) [extracellular region]
(R-HSA-1604726)
MMP9(20-59) [extracellular region]
(R-HSA-1604685)
MMP9(20-106) [extracellular region]
(R-HSA-1604713)
MMP9(20-707) [extracellular region]
(R-HSA-1604376)
MMP9(107-707) [extracellular region]
(R-HSA-668812)
0.527
2
UniProt:P08253 MMP2
5
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(110-660) [extracellular region]
(R-HSA-381456)
0.527
2
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