Reactome | LAMB1 [extracellular region]

LAMB1 [extracellular region]

Stable Identifier

R-HSA-215959

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Laminin beta-1 chain

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P07942 LAMB1

Gene Names

LAMB1

Chain

signal peptide:1-21, chain:22-1786

Reference Genes

BioGPS Gene:3912 LAMB1

COSMIC (genes):LAMB1 LAMB1

CTD Gene:3912 LAMB1

dbSNP Gene:3912 LAMB1

ENSEMBL:ENSG00000091136 LAMB1

HGNC:6486 LAMB1

KEGG:hsa:3912 LAMB1

Monarch:3912 LAMB1

NCBI Gene:3912 LAMB1

OMIM:150240 LAMB1

UCSC:P07942 LAMB1

Reference Transcript

RefSeq:NM_002291.2 LAMB1

Other Identifiers

11723487_a_at

11753971_a_at

17061662

201505_PM_at

201505_at

211651_PM_s_at

211651_s_at

238608_PM_at

238608_at

3067299

3067301

3067303

3067304

3067305

3067306

3067307

3067308

3067309

3067310

3067311

3067312

3067313

3067314

3067315

3067316

3067317

3067318

3067319

3067320

3067321

3067322

3067323

3067324

3067325

3067326

3067327

3067328

3067329

3067330

3067331

3067332

3067333

3067334

3067335

3067336

3067337

3067339

3067346

3067347

3067348

3067349

3067351

3067353

3067354

3067357

3067358

3067359

3067360

3067361

3067362

3067363

3067364

3067365

3067366

3067367

3067370

3067371

3067372

3067373

3067375

3067378

3067379

3067382

3067385

3067386

3067397

3067398

3067399

3067400

3067401

3067402

3067403

3104378

3215253

3912

52426_at

581_at

8142194

84560_at

A_23_P94030

A_33_P3370930

A_33_P3370940

GE596194

GE79227

GO:0005198

GO:0005201

GO:0005515

GO:0005576

GO:0005604

GO:0005606

GO:0005607

GO:0005615

GO:0005788

GO:0007155

GO:0021812

GO:0030154

GO:0030312

GO:0030335

GO:0031012

GO:0031175

GO:0034446

GO:0035987

GO:0042476

GO:0043226

GO:0043257

GO:0043259

GO:0045785

GO:0048471

GO:0050679

GO:0051149

GO:0062023

GO:0070062

GO:0098637

GO:0110011

GO:2001046

HMNXSV003002218

HMNXSV003044214

HMNXSV003050602

Hs.30237.0.A1_3p_at

ILMN_1658709

ILMN_2214790

M61916_at

PH_hs_0022359

TC07001747.hg

g186914_3p_s_at

g4504950_3p_at

Participates

as a component of

Other forms of this molecule

p-LAMB1 [endoplasmic reticulum lumen]

LAMB1 [endoplasmic reticulum lumen]

Inferred To

MEGF6 [extracellular region] (Bos taurus)

MEGF6 [extracellular region] (Canis familiaris)

MEGF6 [extracellular region] (Sus scrofa)

LAMB1 [extracellular region] (Caenorhabditis elegans)

Megf6 [extracellular region] (Mus musculus)

Megf6 [extracellular region] (Rattus norvegicus)

Cross References

ENSEMBL

ENSG00000091136, ENST00000222399, ENSP00000222399

OpenTargets

ENSG00000091136

GeneCards

LAMB1

HPA

ENSG00000091136-LAMB1

PRO

P07942

Pharos - Targets

P07942

GlyGen

P07942

Orphanet

LAMB1

PDB

8DMK, 7CEC, 5XAU

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P59665 DEFA1	9	DEFA1(1-94) [Golgi lumen] (R-HSA-1467215) DEFA1(20-94) [Golgi lumen] (R-HSA-1467282) DEFA1(66-94) [Golgi lumen] (R-HSA-975663) DEFA1(20-65) [Golgi lumen] (R-HSA-8864970) DEFA1(66-94) [extracellular region] (R-HSA-1461998) DEFA1(66-94) [azurophil granule lumen] (R-HSA-1470038) DEFA1(65-94) [extracellular region] (R-HSA-1462022) omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region] (R-HSA-1972397) DEFA1(65-94) [azurophil granule lumen] (R-HSA-1470053)	0.527	2
UniProt:P17931 LGALS3	3	LGALS3 [plasma membrane] (R-HSA-879445) LGALS3 [secretory granule membrane] (R-HSA-6803327) LGALS3 [ficolin-1-rich granule membrane] (R-HSA-6803307)	0.527	3

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