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CSE-CSPG4 [Golgi lumen]
Stable Identifier
R-HSA-2064166
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
_CSPG4, Chondroitin sulfate proteoglycan 4, CSPG4_HUMAN, CSPG4
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)
Chondroitin sulfate biosynthesis (Homo sapiens)
CSPG is secreted (Homo sapiens)
CSPGs [Golgi lumen] (Homo sapiens)
CSE-PG [Golgi lumen] (Homo sapiens)
CSE-CSPG4 [Golgi lumen] (Homo sapiens)
Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Homo sapiens)
CSE-PG [Golgi lumen] (Homo sapiens)
CSE-CSPG4 [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6UVK1 CSPG4
Gene Names
CSPG4, MCSP
Chain
signal peptide:1-29, chain:30-2322
Reference Genes
BioGPS Gene:1464 CSPG4
COSMIC (genes):CSPG4 CSPG4
CTD Gene:1464 CSPG4
dbSNP Gene:1464 CSPG4
ENSEMBL:ENSG00000173546 CSPG4
ENSEMBL_homo_sapiens_GENE:ENSG00000173546.7 CSPG4
HGNC:2466 CSPG4
KEGG Gene (Homo sapiens):1464 CSPG4
Monarch:1464 CSPG4
NCBI Gene:1464 CSPG4
OMIM:601172 CSPG4
UCSC:Q6UVK1 CSPG4
Reference Transcript
RefSeq:NM_001897.4 CSPG4
Other Identifiers
110_at
11739547_at
11739548_at
1464
16811858
17121214
17121220
204736_PM_s_at
204736_s_at
214297_PM_at
214297_at
3603037
3603038
3603045
3603046
3603052
3603053
3603058
3603081
3604691
3604754
3604759
3604841
3604889
3605115
3606195
3633579
3633580
3633582
3633584
3633585
3633586
3633591
3633593
3633594
3633595
3633596
3633598
3633607
3633608
3636033
3636789
38004_at
4038921
4039468
7990545
A_23_P21976
GE60186
GO:0001525
GO:0001726
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005764
GO:0005773
GO:0005794
GO:0005796
GO:0005886
GO:0005925
GO:0006929
GO:0007165
GO:0008347
GO:0009986
GO:0015026
GO:0016020
GO:0016324
GO:0019901
GO:0023052
GO:0030154
GO:0030312
GO:0031012
GO:0031258
GO:0035556
GO:0036211
GO:0042995
GO:0043202
GO:0043226
GO:0043410
GO:0048008
GO:0048771
GO:0048856
GO:0048870
GO:0050731
GO:0060089
GO:0062023
GO:0070062
GO:0097178
HMNXSV003051518
Hs.9004.1.S1_3p_at
ILMN_1666894
PH_hs_0025491
TC15001670.hg
X96753_at
g4503098_3p_a_at
Participates
as a member of
CSE-PG [Golgi lumen] (Homo sapiens)
Other forms of this molecule
CSPG4 [plasma membrane]
dermatan-CSPG4 [Golgi lumen]
D2,4(S)2-CSPG4 [Golgi lumen]
D2,4,4(S)3-CSPG4 [Golgi lumen]
D4S-CSPG4 [Golgi lumen]
CSE-CSPG4 [lysosomal lumen]
C6S-CSPG4 [lysosomal lumen]
C4S-CSPG4 [lysosomal lumen]
D2,4(S)2-CSPG4 [lysosomal lumen]
D4S-CSPG4 [lysosomal lumen]
D4S-CSPG4 [extracellular region]
D2,4(S)2-CSPG4 [extracellular region]
D2,4,4(S)3-CSPG4 [extracellular region]
CSPG4 [lysosomal lumen]
D2,4,4(S)3-CSPG4 [lysosomal lumen]
CSE-CSPG4 [extracellular region]
C6S-CSPG4 [extracellular region]
C4S-CSPG4 [extracellular region]
Gal-Gal-Xyl-CSPG4 [Golgi lumen]
GlcA-Gal-Gal-Xyl-CSPG4 [Golgi lumen]
Gal-Xyl-CSPG4 [Golgi lumen]
XylS-CSPG4 [Golgi lumen]
CSPG4 [Golgi lumen]
chondroitin(1)-CSPG4 [Golgi lumen]
chondroitin(2)-CSPG4 [Golgi lumen]
chondroitin(3)-CSPG4 [Golgi lumen]
C4S-CSPG4 [Golgi lumen]
C6S-CSPG4 [Golgi lumen]
Inferred To
CSPG4 [Golgi lumen]
(Bos taurus)
CSPG4 [Golgi lumen]
(Canis familiaris)
CSPG4 [Golgi lumen]
(Sus scrofa)
Cspg4 [Golgi lumen]
(Mus musculus)
Cspg4 [Golgi lumen]
(Rattus norvegicus)
kon [Golgi lumen]
(Drosophila melanogaster)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63515) at unknown position
Modification
beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc4,6S2-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
NP_001888.2
OpenTargets
ENSG00000173546
HPA
ENSG00000173546-CSPG4
GeneCards
Q6UVK1
Ensembl
ENSG00000173546
,
ENSP00000312506
,
ENST00000308508
PRO
Q6UVK1
Pharos - Targets
Q6UVK1
HMDB Protein
HMDBP10791
PDB
7N8X
,
7ML7
,
7N9Y
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
LGALS3 [plasma membrane]
(R-HSA-879445)
0.527
4
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