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CSPG4 [lysosomal lumen]
Stable Identifier
R-HSA-2065223
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal lumen
Synonyms
Chondroitin sulfate proteoglycan 4, CSPG4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Chondroitin sulfate/dermatan sulfate metabolism (Homo sapiens)
CS/DS degradation (Homo sapiens)
CS is cleaved from its proteoglycan (Homo sapiens)
CS/DS core proteins [lysosomal lumen] (Homo sapiens)
CSPG4 [lysosomal lumen] (Homo sapiens)
DS is cleaved from its proteoglycan (Homo sapiens)
CS/DS core proteins [lysosomal lumen] (Homo sapiens)
CSPG4 [lysosomal lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6UVK1 CSPG4
Gene Names
CSPG4, MCSP
Chain
signal peptide:1-29, chain:30-2322
Reference Genes
BioGPS Gene:1464 CSPG4
COSMIC (genes):CSPG4 CSPG4
CTD Gene:1464 CSPG4
dbSNP Gene:1464 CSPG4
ENSEMBL:ENSG00000173546 CSPG4
HGNC:2466 CSPG4
KEGG:hsa:1464 CSPG4
Monarch:1464 CSPG4
NCBI Gene:1464 CSPG4
OMIM:601172 CSPG4
UCSC:Q6UVK1 CSPG4
Reference Transcript
RefSeq:NM_001897.4 CSPG4
Other Identifiers
110_at
11739547_at
11739548_at
1464
16811858
17121214
17121220
204736_PM_s_at
204736_s_at
214297_PM_at
214297_at
3603037
3603045
3603046
3603052
3603053
3603058
3603081
3604759
3604841
3604889
3605115
3606195
3633579
3633580
3633582
3633584
3633585
3633586
3633591
3633593
3633594
3633595
3633596
3633598
3633607
3633608
3636033
3636789
38004_at
4038921
4039468
7990545
A_23_P21976
GE60186
GO:0001525
GO:0001726
GO:0005576
GO:0005654
GO:0005796
GO:0005886
GO:0005925
GO:0006929
GO:0007165
GO:0008347
GO:0009986
GO:0015026
GO:0016324
GO:0019901
GO:0030154
GO:0030312
GO:0031012
GO:0031258
GO:0035556
GO:0042995
GO:0043202
GO:0043226
GO:0043410
GO:0048008
GO:0048771
GO:0048870
GO:0050731
GO:0060089
GO:0062023
GO:0070062
GO:0097178
HMNXSV003051518
Hs.9004.1.S1_3p_at
ILMN_1666894
PH_hs_0025491
TC15001670.hg
X96753_at
g4503098_3p_a_at
Participates
as a member of
CS/DS core proteins [lysosomal lumen] (Homo sapiens)
Other forms of this molecule
XylS-CSPG4 [Golgi lumen]
Gal-Xyl-CSPG4 [Golgi lumen]
CSPG4 [Golgi lumen]
Gal-Gal-Xyl-CSPG4 [Golgi lumen]
GlcA-Gal-Gal-Xyl-CSPG4 [Golgi lumen]
D2,4(S)2-CSPG4 [Golgi lumen]
dermatan-CSPG4 [Golgi lumen]
D4S-CSPG4 [Golgi lumen]
D2,4,4(S)3-CSPG4 [Golgi lumen]
chondroitin(3)-CSPG4 [Golgi lumen]
C4S-CSPG4 [Golgi lumen]
chondroitin(2)-CSPG4 [Golgi lumen]
chondroitin(1)-CSPG4 [Golgi lumen]
D2,4,4(S)3-CSPG4 [extracellular region]
D2,4(S)2-CSPG4 [extracellular region]
D4S-CSPG4 [extracellular region]
C6S-CSPG4 [Golgi lumen]
CSE-CSPG4 [Golgi lumen]
C4S-CSPG4 [extracellular region]
C6S-CSPG4 [extracellular region]
CSE-CSPG4 [extracellular region]
C4S-CSPG4 [lysosomal lumen]
C6S-CSPG4 [lysosomal lumen]
CSE-CSPG4 [lysosomal lumen]
D4S-CSPG4 [lysosomal lumen]
D2,4(S)2-CSPG4 [lysosomal lumen]
D2,4,4(S)3-CSPG4 [lysosomal lumen]
CSPG4 [plasma membrane]
Inferred To
Cspg4 [lysosomal lumen]
(Mus musculus)
Cspg4 [lysosomal lumen]
(Rattus norvegicus)
CSPG4 [lysosomal lumen]
(Bos taurus)
CSPG4 [lysosomal lumen]
(Canis familiaris)
CSPG4 [lysosomal lumen]
(Sus scrofa)
kon [lysosomal lumen]
(Drosophila melanogaster)
Cross References
OpenTargets
ENSG00000173546
ENSEMBL
ENSP00000312506
HPA
ENSG00000173546-CSPG4
PRO
Q6UVK1
Pharos - Targets
Q6UVK1
GlyGen
Q6UVK1
HMDB Protein
HMDBP10791
PDB
7ML7
,
7N8X
,
7N9Y
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P17931 LGALS3
3
LGALS3 [ficolin-1-rich granule membrane]
(R-HSA-6803307)
LGALS3 [plasma membrane]
(R-HSA-879445)
LGALS3 [secretory granule membrane]
(R-HSA-6803327)
0.527
4
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