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SFKs:p-KIT complex [plasma membrane]
Stable Identifier
R-HSA-205271
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
SFKs:p-7Y-KIT:sSCF dimer:p-7Y-KIT
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Dimerization of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Disassociation and translocation of STATs to the nucleus (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2 is indirectly recruited to p-KIT through SHP2 (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Indirect recruitment of GAB2 to p-KIT (Homo sapiens)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Homo sapiens)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Interaction of Src family kinases with p-KIT (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
JAK2 binds to p-KIT (Homo sapiens)
JAK2:SFKS:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation and activation of VAV1 (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of GAB2 by SFKs (Homo sapiens)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of JAK2 (Homo sapiens)
JAK2:SFKS:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of SHP2 by SFKs (Homo sapiens)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of p-KIT on Y900 by Src kinases (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Recruitment of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Regulation of KIT signaling (Homo sapiens)
Interaction of APS and p-KIT (Homo sapiens)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Phosphorylation of APS (Homo sapiens)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
p-APS dimer:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Recruitment of CBL to KIT (Homo sapiens)
CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Homo sapiens)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Homo sapiens)
p-APS dimer:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Homo sapiens)
p-APS dimer:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SHP2 interacts with p-KIT (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
Participants
components
p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]
(Homo sapiens)
Src family tyrosine kinases (SFKs) [cytosol]
(Homo sapiens)
Participates
as an input of
Phosphorylation of p-KIT on Y900 by Src kinases (Homo sapiens)
JAK2 binds to p-KIT (Homo sapiens)
Interaction of APS and p-KIT (Homo sapiens)
SHP2 interacts with p-KIT (Homo sapiens)
as a component of
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Homo sapiens)
JAK2:SFKS:p-KIT complex [plasma membrane] (Homo sapiens)
p-APS dimer:p-KIT complex [plasma membrane] (Homo sapiens)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Homo sapiens)
p-SHP2:p-KIT complex [plasma membrane] (Homo sapiens)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Homo sapiens)
as an output of
Interaction of Src family kinases with p-KIT (Homo sapiens)
Inferred To
SFKs:p-KIT complex [plasma membrane]
(Bos taurus)
SFKs:p-KIT complex [plasma membrane]
(Canis familiaris)
SFKs:p-KIT complex [plasma membrane]
(Danio rerio)
SFKs:p-KIT complex [plasma membrane]
(Drosophila melanogaster)
SFKs:p-KIT complex [plasma membrane]
(Gallus gallus)
SFKs:p-KIT complex [plasma membrane]
(Mus musculus)
SFKs:p-KIT complex [plasma membrane]
(Rattus norvegicus)
SFKs:p-KIT complex [plasma membrane]
(Sus scrofa)
SFKs:p-KIT complex [plasma membrane]
(Xenopus tropicalis)
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