APS adapter protein has been identified as a KIT binding partner using yeast two-hybrid screening. APS contains a PH domain and an SH2 domain. The SH2 domain interacts with c-Kit phosphotyrosine residues Y568 and Y936 (Wollberg et al. 2003).
Wollberg, P, Yoshimura, A, Gottfridsson, E, Lennartsson, J, Rönnstrand, L
© 2022 Reactome