Interaction of APS and p-KIT

Stable Identifier
R-HSA-205319
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
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Interaction of APS and p-KIT
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APS adapter protein has been identified as a KIT binding partner using yeast two-hybrid screening. APS contains a PH domain and an SH2 domain. The SH2 domain interacts with c-Kit phosphotyrosine residues Y568 and Y936 (Wollberg et al. 2003).

Literature References
PubMed ID Title Journal Year
12444928 The adapter protein APS associates with the multifunctional docking sites Tyr-568 and Tyr-936 in c-Kit

Wollberg, P, Lennartsson, J, Gottfridsson, E, Yoshimura, A, Rönnstrand, L

Biochem J 2003
Participants
Input
Output
Participant Of
hasEvent
Orthologous Events
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Interaction of APS and p-KIT (Sus scrofa)
Interaction of APS and p-KIT (Xenopus tropicalis)
Authored
Garapati, P V  (2011-07-11)
Reviewed
Rönnstrand, L  (2011-08-22)
Created
Garapati, P V  (2007-12-10)
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