Dimerized phospho-IRF3 migrates to the nucleus

Stable Identifier
R-HSA-2032396
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, nuclear envelope, nucleoplasm
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Dimerized phospho-IRF3 migrates to the nucleus
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

IRF3-P:IRF3-P' is translocated from cytosol to nucleoplasm.

Literature References
PubMed ID Title Journal Year
12692549 IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

Fitzgerald, KA, McWhirter, SM, Faia, KL, Rowe, DC, Latz, E, Golenbock, DT, Coyle, AJ, Liao, SM, Maniatis, T

Nat Immunol 2003
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Authored
Shamovsky, V  (2011-09-21)
Reviewed
D'Eustachio, P  (2011-12-07)
Upton, JW  (2012-02-19)
Mocarski, ES  (2012-02-19)
Jin, L  (2012-08-18)
Wu, J  (2013-05-21)
Created
Shamovsky, V  (2012-01-06)