Reactome | Dimerized phospho-IRF3 migrates to the nucleus

Dimerized phospho-IRF3 migrates to the nucleus

Stable Identifier

R-HSA-2032396

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol, nuclear envelope, nucleoplasm

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Dimerized phospho-IRF3 migrates to the nucleus

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IRF3-P:IRF3-P' is translocated from cytosol to nucleoplasm.

Literature References

PubMed ID	Title	Journal	Year
12692549	IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway Fitzgerald, KA, McWhirter, SM, Faia, KL, Rowe, DC, Latz, E, Golenbock, DT, Coyle, AJ, Liao, SM, Maniatis, T	Nat Immunol	2003