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3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-2023657
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
4-Hyp Glu-Gal-Hyl collagen alpha-2(IV) propeptide
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Collagen biosynthesis and modifying enzymes (Homo sapiens)
Collagen chain trimerization (Homo sapiens)
Association of procollagen type IV (Homo sapiens)
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-1(IV)X2 alpha-2(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
Glucosylation of collagen propeptide hydroxylysines (Homo sapiens)
PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp Glu-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Homo sapiens)
Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp Glu-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum membrane] (Homo sapiens)
Glucosyl-galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
4-Hyp Glu-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen triple helix formation (Homo sapiens)
Collagen and procollagen triple helices:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagen and procollagen triple helices [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-1(IV)X2 alpha-2(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
Procollagen C-linked trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen type IV trimers [endoplasmic reticulum lumen] (Homo sapiens)
C-linked procollagen alpha-1(IV)X2 alpha-2(IV) trimer [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
Secretion of collagens (Homo sapiens)
Collagens and tropocollagens:Serpin H1 [endoplasmic reticulum lumen] (Homo sapiens)
Collagens and tropocollagens [endoplasmic reticulum lumen] (Homo sapiens)
Non-fibrillar collagens [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen type IV [endoplasmic reticulum lumen] (Homo sapiens)
Tropocollagen alpha-1(IV)X2 alpha-2(IV) [endoplasmic reticulum lumen] (Homo sapiens)
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08572 COL4A2
Gene Names
COL4A2
Chain
signal peptide:1-25, propeptide:26-183, chain:184-1712, chain:1486-1712
Reference Genes
BioGPS Gene:1284 COL4A2
COSMIC (genes):COL4A2 COL4A2
CTD Gene:1284 COL4A2
dbSNP Gene:1284 COL4A2
ENSEMBL:ENSG00000134871 COL4A2
ENSEMBL_homo_sapiens_GENE:ENSG00000134871.19 COL4A2
HGNC:2203 COL4A2
KEGG Gene (Homo sapiens):1284 COL4A2
Monarch:1284 COL4A2
NCBI Gene:1284 COL4A2
OMIM:120090 COL4A2
UCSC:P08572 COL4A2
Reference Transcript
RefSeq:NM_001846.3 COL4A2
Other Identifiers
11715451_a_at
11715452_s_at
11715453_a_at
1284
16776431
211964_PM_at
211964_at
211966_PM_at
211966_at
3501224
3501225
3501226
3501227
3501247
3501263
3501264
3501266
3501268
3501269
3501270
3501273
3501275
3501278
3501279
3501280
3501282
3501286
3501289
3501293
3501295
3501300
3501301
3501305
3501306
3501308
3501310
3501311
3501312
3501316
3501317
3501318
3501327
3501328
3501329
3501331
3501332
3501333
3501334
3501335
3501337
3501339
3501340
3501343
3501346
3501348
3501349
3501350
3501351
3501352
3501355
3501356
3501359
3501360
3501363
3501364
3501365
3501366
3501367
3501368
3501369
36659_at
70626_at
7970033
A_14_P118100
A_23_P205031
GE59670
GE86395
GO:0001525
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0006351
GO:0014823
GO:0016525
GO:0023052
GO:0030020
GO:0030154
GO:0030198
GO:0030312
GO:0031012
GO:0035987
GO:0038063
GO:0043226
GO:0048856
GO:0060090
GO:0062023
GO:0070062
GO:0071560
HMNXSV003050909
Hs.75617.0.A1_3p_at
Hs.75617.0.A2_3p_at
ILMN_1724994
M24766_s_at
PH_hs_0024713
TC13000392.hg
TC13001293.hg
X05610_at
Participates
as a candidate of
4-Hyp Glu-Gal-Hyl collagen propeptides [endoplasmic reticulum lumen] (Homo sapiens)
as a member of
Alpha-2(IV) chains [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
3x4Hyp-3Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
GalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
5Hyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
3,4-Hyp 5-sulfiniminyl collagen alpha-2(IV) chain [extracellular region]
4-Hyp 5-sulfiniminyl collagen alpha-2(IV) chain [extracellular region]
5-sulfiniminyl collagen alpha-2(IV) chain [extracellular region]
GalHyl-COL4A2(26-?) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A2(26-?) [extracellular region]
3x4Hyp-GalHyl-COL4A2(?-1712) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A2(26-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A2(26-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A2(?-1712) [extracellular region]
5Hyl-COL4A2(26-?) [extracellular region]
5Hyl-COL4A2(?-1712) [extracellular region]
GlcGalHyl-COL4A2(26-?) [extracellular region]
GlcGalHyl-COL4A2(?-1712) [extracellular region]
3,4-Hyp 5-Gal-Hyl collagen alpha-2(IV) chain C-term fragment [extracellular region]
3x4Hyp-5Hyl-COL4A2(?-1712) [extracellular region]
COL4A2(26-?) [extracellular region]
3x4Hyp-3Hyp-COL4A2(?-1712) [extracellular region]
GalHyl-COL4A2(?-1712) [extracellular region]
3x4Hyp-3Hyp-COL4A2(26-?) [extracellular region]
3x4Hyp-COL4A2(?-1712) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A2(26-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A2(?-1712) [extracellular region]
3x4Hyp-5Hyl-COL4A2(26-?) [extracellular region]
3x4Hyp-GalHyl-COL4A2(26-?) [extracellular region]
3x4Hyp-COL4A2(26-?) [extracellular region]
COL4A2(?-1712) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A2(?-1712) [extracellular region]
3x4Hyp-COL4A2(1486-1712) [extracellular region]
5Hyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-5Hyl-COL4A2(1486-1712) [extracellular region]
COL4A2(1486-1712) [extracellular region]
GalHyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-3Hyp-COL4A2(1486-1712) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A2(1486-1712) [extracellular region]
COL4A2(184-1712) [extracellular region]
3x4Hyp-COL4A2(184-1712) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-GalHyl-COL4A2(184-1712) [extracellular region]
5Hyl-COL4A2(184-1712) [extracellular region]
GlcGalHyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-5Hyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A2(184-1712) [extracellular region]
GalHyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A2(184-1712) [extracellular region]
3x4Hyp-3Hyp-COL4A2(184-1712) [extracellular region]
GlcGalHyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-GalHyl-COL4A2(1486-1712) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A2(1486-1712) [extracellular region]
Inferred To
Col4a2 [endoplasmic reticulum lumen]
(Mus musculus)
Col4a2 [endoplasmic reticulum lumen]
(Rattus norvegicus)
let-2 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
emb-9 [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
COL4A2 [endoplasmic reticulum lumen]
(Canis familiaris)
COL4A2 [endoplasmic reticulum lumen]
(Sus scrofa)
col4a2 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
(Bos taurus)
3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
(Gallus gallus)
Homologues of 3x4Hyp-GlcGalHyl-COL4A2(26-1712) [endoplasmic reticulum lumen]
(Caenorhabditis elegans)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
O5-glucosylgalactosyl-L-hydroxylysine at unknown position
PsiMod Name
O5-glucosylgalactosyl-L-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to O5-glucosylgalactosyl-L-hydroxylysine.
Cross References
RefSeq
NP_001837.2
OpenTargets
ENSG00000134871
HPA
ENSG00000134871-COL4A2
GeneCards
P08572
Ensembl
ENSP00000353654
,
ENSG00000134871
,
ENST00000360467
PRO
P08572
Pharos - Targets
P08572
Orphanet
20792
PDB
6MPX
,
5NB2
,
1LI1
,
5NAX
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14780 MMP9
8
MMP9 [ficolin-1-rich granule lumen]
(R-HSA-6800973)
MMP9 [tertiary granule lumen]
(R-HSA-6800181)
MMP9(60-106) [extracellular region]
(R-HSA-1604699)
MMP9(60-707) [extracellular region]
(R-HSA-1604726)
MMP9(20-59) [extracellular region]
(R-HSA-1604685)
MMP9(20-106) [extracellular region]
(R-HSA-1604713)
MMP9(20-707) [extracellular region]
(R-HSA-1604376)
MMP9(107-707) [extracellular region]
(R-HSA-668812)
0.527
2
UniProt:P08253 MMP2
5
MMP2(67-109) [extracellular region]
(R-HSA-1604371)
MMP2(67-660) [extracellular region]
(R-HSA-1604345)
MMP2(30-66) [extracellular region]
(R-HSA-1604347)
MMP2(30-660) [extracellular region]
(R-HSA-1604364)
MMP2(110-660) [extracellular region]
(R-HSA-381456)
0.527
2
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