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BAG6 [cytosol]
Stable Identifier
R-HSA-201567
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
BAT3
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane (Homo sapiens)
BAG6:GET4:UBL4A binds mislocalized membrane protein:SGTA and ASNA1:ATP (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
Mislocalized membrane protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP [cytosol] (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA dimer binds BAG6:GET4:UBL4A and ASNA1:ATP (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP [cytosol] (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP [cytosol] (Homo sapiens)
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
BAG6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P46379 BAG6
Gene Names
BAG6, BAT3, G3
Chain
chain:1-1132
Reference Genes
BioGPS Gene:7917 BAG6
COSMIC (genes):BAG6 BAG6
CTD Gene:7917 BAG6
dbSNP Gene:7917 BAG6
ENSEMBL:ENSG00000204463 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000096155.15 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000204463.14 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000227761.10 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000228760.10 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000229524.10 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000233348.10 BAG6
ENSEMBL_homo_sapiens_GENE:ENSG00000234651.10 BAG6
HGNC:13919 BAG6
KEGG Gene (Homo sapiens):7917 BAG6
Monarch:7917 BAG6
NCBI Gene:7917 BAG6
OMIM:142590 BAG6
UCSC:P46379 BAG6
Reference Transcript
RefSeq:NM_001098534.1 BAG6
RefSeq:XM_017011287.1 BAG6
RefSeq:NM_080703.2 BAG6
RefSeq:NM_080702.2 BAG6
RefSeq:NM_004639.3 BAG6
RefSeq:NM_001199698.1 BAG6
RefSeq:NM_001199697.1 BAG6
Other Identifiers
11719735_a_at
11727634_x_at
11744473_x_at
17017244
17029102
17031887
17034357
17036605
17039400
17041883
201255_PM_x_at
201255_x_at
210208_PM_x_at
210208_x_at
213318_PM_s_at
213318_s_at
2949149
2949150
2949152
2949155
2949157
2949158
2949160
2949162
2949163
2949165
2949166
2949167
2949168
2949170
2949171
2949172
2949173
2949176
2949178
2949180
2949181
2949182
2949184
2949186
2949188
2949189
2949190
2949194
2949195
2949196
33838_at
7917
8124967
8178526
8179782
A_24_P608411
A_33_P3275668
GE81422
GO:0001822
GO:0002376
GO:0002429
GO:0005102
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006325
GO:0006511
GO:0006620
GO:0006886
GO:0006915
GO:0007059
GO:0007130
GO:0007283
GO:0007420
GO:0010498
GO:0012501
GO:0016020
GO:0018393
GO:0022414
GO:0023052
GO:0030101
GO:0030154
GO:0030163
GO:0030324
GO:0030433
GO:0030544
GO:0031593
GO:0031625
GO:0031647
GO:0032435
GO:0036211
GO:0036503
GO:0036506
GO:0042771
GO:0042802
GO:0042981
GO:0043022
GO:0043066
GO:0043161
GO:0043226
GO:0043231
GO:0045861
GO:0045995
GO:0048856
GO:0050821
GO:0051787
GO:0061024
GO:0061857
GO:0070059
GO:0070062
GO:0070628
GO:0071712
GO:0071816
GO:0071818
GO:0140013
GO:1904294
GO:1990381
HMNXSV003010413
Hs.274348.2.S1_3p_a_at
ILMN_1705364
ILMN_2390416
M33521_at
TC06001532.hg
TC6_cox_hap2000161.hg
TC6_dbb_hap3000150.hg
TC6_mann_hap4000138.hg
TC6_mcf_hap5000138.hg
TC6_qbl_hap6000153.hg
TC6_ssto_hap7000133.hg
Participates
as a component of
BAG6:GET4:UBL4A [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_001186626.1
,
NP_001186627.1
,
NP_004630.3
,
NP_542434.1
,
NP_542433.1
,
XP_016866776.1
,
NP_001092004.1
OpenTargets
ENSG00000204463
GeneCards
P46379
HPA
ENSG00000204463-BAG6
Ensembl
ENSP00000390966
,
ENSP00000447946
,
ENSP00000372940
,
ENST00000443182
,
ENST00000552605
,
ENST00000613474
,
ENSG00000233348
,
ENST00000551350
,
ENST00000621056
,
ENSP00000412110
,
ENST00000552116
,
ENSG00000204463
,
ENSP00000478966
,
ENSP00000446525
,
ENSG00000227761
,
ENST00000617635
,
ENST00000615143
,
ENSP00000502941
,
ENSG00000234651
,
ENSP00000484238
,
ENST00000419847
,
ENSP00000365143
,
ENST00000375976
,
ENST00000362049
,
ENST00000449450
,
ENST00000451932
,
ENSP00000447546
,
ENST00000417144
,
ENST00000442479
,
ENSP00000372938
,
ENST00000361076
,
ENSP00000354875
,
ENST00000383446
,
ENSP00000389121
,
ENSP00000477951
,
ENST00000439687
,
ENSP00000211379
,
ENSP00000479238
,
ENST00000211379
,
ENSP00000482413
,
ENSP00000397894
,
ENSP00000413698
,
ENSG00000228760
,
ENSP00000402856
,
ENSP00000477867
,
ENSG00000096155
,
ENSP00000354368
,
ENST00000615725
,
ENSP00000410156
,
ENST00000615224
,
ENST00000676615
,
ENST00000383448
,
ENSG00000229524
PRO
P46379
Pharos - Targets
P46379
PDB
7RUC
,
4DWF
,
2N9P
,
4X86
,
7RU9
,
1WX9
,
7RUA
,
4WWR
,
6AU8
,
4EEW
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P11802 CDK4
3
CDK4 [cytosol]
(R-HSA-68330)
CDK4 [nucleoplasm]
(R-HSA-113843)
p-T172-CDK4 [nucleoplasm]
(R-HSA-113830)
0.573
2
UniProt:Q7Z434 MAVS
2
MAVS [mitochondrial outer membrane]
(R-HSA-913730)
K48polyUb-MAVS [mitochondrial outer membrane]
(R-HSA-983463)
0.499
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
8
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