Reactome | TLL1 [extracellular region]

TLL1 [extracellular region]

Stable Identifier

R-HSA-2002443

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Tolloid-like protein 1, TLL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43897 TLL1

Gene Names

TLL1, TLL

Chain

signal peptide:1-30, propeptide:31-147, chain:148-1013

Reference Genes

BioGPS Gene:7092 TLL1

COSMIC (genes):TLL1 TLL1

CTD Gene:7092 TLL1

dbSNP Gene:7092 TLL1

ENSEMBL:ENSG00000038295 TLL1

HGNC:11843 TLL1

Monarch:7092 TLL1

NCBI Gene:7092 TLL1

OMIM:606742 TLL1

UCSC:O43897 TLL1

Reference Transcript

Other Identifiers

11737086_a_at

11737087_at

11737088_at

11737089_a_at

11762620_at

1555071_PM_at

1555071_at

16972198

206415_PM_at

206415_at

2750755

2750756

2750757

2750758

2750759

2750760

2750761

2750766

2750767

2750774

2750787

2750788

2750789

2750790

2750791

2750792

2750793

2750795

2750799

2750801

2750804

2750805

2750806

2750807

2750808

2750811

2750812

2750814

2750815

2750816

2750817

2750818

2750819

2750824

2750829

2750832

2750833

2750834

2750835

2750836

31333_at

7092

8098214

86964_at

A_14_P101657

A_14_P109377

A_14_P122103

A_14_P127810

A_21_P0000156

A_23_P427645

A_24_P145163

GE473790

GE475997

GO:0001501

GO:0003824

GO:0004222

GO:0004252

GO:0005509

GO:0005576

GO:0005615

GO:0006508

GO:0008237

GO:0008270

GO:0009953

GO:0016020

GO:0016485

GO:0016787

GO:0030154

GO:0030198

GO:0030199

GO:0046872

GO:0048856

GO:0051604

GO:0140096

HMNXSV003008314

HMNXSV003048717

Hs.129700.0.S3_3p_at

Hs2.129700.2.S1_3p_at

ILMN_1699814

PH_hs_0007588

TC04000833.hg

Participates

as a member of

Inferred To

TLL1 [extracellular region] (Bos taurus)

TLL1 [extracellular region] (Caenorhabditis elegans)

TLL1 [extracellular region] (Canis familiaris)

TLL1 [extracellular region] (Danio rerio)

TLL1 [extracellular region] (Drosophila melanogaster)

TLL1 [extracellular region] (Mus musculus)

TLL1 [extracellular region] (Rattus norvegicus)

TLL1 [extracellular region] (Sus scrofa)

Homologues of TLL1 [extracellular region] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000061240, ENST00000513213, ENSP00000061240, ENSP00000422937

OpenTargets

ENSG00000038295

HPA

ENSG00000038295-TLL1

PRO

O43897

Pharos - Targets

O43897

Orphanet

TLL1

PDB

3EDI

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
calcium(2+) [ChEBI:29108]	20	Ca2+ [platelet dense granule lumen] (R-ALL-114582) Ca2+ [endosome membrane] (R-ALL-5210949) Ca2+ [sarcoplasmic reticulum lumen] (R-ALL-2855229) Ca2+ [mitochondrial intermembrane space] (R-ALL-8949232) Ca2+ [lysosomal lumen] (R-ALL-1606834) Ca2+ [endocytic vesicle lumen] (R-ALL-8851519) Ca2+ [endoplasmic reticulum-Golgi intermediate compartment] (R-ALL-9706979) Ca2+ [Golgi lumen] (R-ALL-167012) Ca2+ [platelet dense tubular network lumen] (R-ALL-139827) Ca2+ [platelet dense tubular network membrane] (R-ALL-141090) Ca2+ [plasma membrane] (R-ALL-140648) Ca2+ [secretory granule lumen] (R-ALL-216801) Ca2+ [nuclear envelope] (R-ALL-2318767) Ca2+ [nucleoplasm] (R-ALL-29496) Ca2+ [mitochondrial matrix] (R-ALL-8949220) Ca2+ [mitochondrial inner membrane] (R-ALL-1524102) Ca2+ [endoplasmic reticulum membrane] (R-ALL-1500625) Ca2+ [cytosol] (R-ALL-74016) Ca2+ [extracellular region] (R-ALL-74112) Ca2+ [endoplasmic reticulum lumen] (R-ALL-111875)	0.544	5