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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
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Developer's Zone
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Pathway Diagrams
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FAQ
Linking to Us
Citing us
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Analyse gene list
Analyse gene expression
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Go!
Ca2+ [nuclear envelope]
Stable Identifier
R-ALL-2318767
Type
Chemical Compound [SimpleEntity]
Compartment
nuclear envelope
Synonyms
Calcium, calcium(2+)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Dictyostelium discoideum
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Biosynthesis of specialized proresolving mediators (SPMs) (Bos taurus)
Biosynthesis of Lipoxins (LX) (Bos taurus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Bos taurus)
Arachidonate metabolism (Bos taurus)
Synthesis of 5-eicosatetraenoic acids (Bos taurus)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Bos taurus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Bos taurus)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Bos taurus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
Ca2+ [nuclear envelope]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Biosynthesis of specialized proresolving mediators (SPMs) (Canis familiaris)
Biosynthesis of Lipoxins (LX) (Canis familiaris)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Canis familiaris)
Arachidonate metabolism (Canis familiaris)
Synthesis of 5-eicosatetraenoic acids (Canis familiaris)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Canis familiaris)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Canis familiaris)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Canis familiaris)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
Ca2+ [nuclear envelope]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Biosynthesis of specialized proresolving mediators (SPMs) (Dictyostelium discoideum)
Biosynthesis of Lipoxins (LX) (Dictyostelium discoideum)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Dictyostelium discoideum)
Arachidonate metabolism (Dictyostelium discoideum)
Synthesis of 5-eicosatetraenoic acids (Dictyostelium discoideum)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Dictyostelium discoideum)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Dictyostelium discoideum)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Dictyostelium discoideum)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
Ca2+ [nuclear envelope]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Biosynthesis of specialized proresolving mediators (SPMs) (Gallus gallus)
Biosynthesis of Lipoxins (LX) (Gallus gallus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Gallus gallus)
Arachidonate metabolism (Gallus gallus)
Synthesis of 5-eicosatetraenoic acids (Gallus gallus)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Gallus gallus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Gallus gallus)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Gallus gallus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
Ca2+ [nuclear envelope]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Biosynthesis of specialized proresolving mediators (SPMs) (Homo sapiens)
Biosynthesis of Lipoxins (LX) (Homo sapiens)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Homo sapiens)
Arachidonate metabolism (Homo sapiens)
Synthesis of 5-eicosatetraenoic acids (Homo sapiens)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Homo sapiens)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Homo sapiens)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Homo sapiens)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Homo sapiens)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Ca2+ [nuclear envelope]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Biosynthesis of specialized proresolving mediators (SPMs) (Mus musculus)
Biosynthesis of Lipoxins (LX) (Mus musculus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Mus musculus)
Arachidonate metabolism (Mus musculus)
Synthesis of 5-eicosatetraenoic acids (Mus musculus)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Mus musculus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Mus musculus)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Mus musculus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
Ca2+ [nuclear envelope]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Biosynthesis of specialized proresolving mediators (SPMs) (Rattus norvegicus)
Biosynthesis of Lipoxins (LX) (Rattus norvegicus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Rattus norvegicus)
Arachidonate metabolism (Rattus norvegicus)
Synthesis of 5-eicosatetraenoic acids (Rattus norvegicus)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Rattus norvegicus)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Rattus norvegicus)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Rattus norvegicus)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
Ca2+ [nuclear envelope]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Biosynthesis of specialized proresolving mediators (SPMs) (Sus scrofa)
Biosynthesis of Lipoxins (LX) (Sus scrofa)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Sus scrofa)
Arachidonate metabolism (Sus scrofa)
Synthesis of 5-eicosatetraenoic acids (Sus scrofa)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Sus scrofa)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Sus scrofa)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Sus scrofa)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
Ca2+ [nuclear envelope]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Biosynthesis of specialized proresolving mediators (SPMs) (Xenopus tropicalis)
Biosynthesis of Lipoxins (LX) (Xenopus tropicalis)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
ALOX5 oxidises 15S-HpETE to LXA4/B4 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
Fatty acid metabolism (Xenopus tropicalis)
Arachidonate metabolism (Xenopus tropicalis)
Synthesis of 5-eicosatetraenoic acids (Xenopus tropicalis)
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Xenopus tropicalis)
5S-HpETE is dehydrated to LTA4 by ALOX5 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
ALOX5 binds ALOX5 inhibitors (Xenopus tropicalis)
ALOX5:ALOX5 inhibitors [nuclear envelope] (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
Arachidonate is oxidised to 5S-HpETE by ALOX5 (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
EXA4 is converted to EXC4 by LTC4S (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
LTA4 is converted to LTC4 by LTC4S (Xenopus tropicalis)
ALOX5:ALOX5AP:LTC4S [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
Ca2+ [nuclear envelope]
External Reference Information
External Reference
calcium(2+) [ChEBI:29108]
Participates
as a component of
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Rattus norvegicus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Mus musculus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Sus scrofa)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Xenopus tropicalis)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Gallus gallus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Dictyostelium discoideum)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Bos taurus)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Canis familiaris)
p-S272-ALOX5:Ca2+:Fe2+ [nuclear envelope] (Homo sapiens)
Other forms of this molecule
Ca2+ [platelet dense granule lumen]
Ca2+ [endosome membrane]
Ca2+ [sarcoplasmic reticulum lumen]
Ca2+ [mitochondrial intermembrane space]
Ca2+ [endocytic vesicle lumen]
Ca2+ [lysosomal lumen]
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
Ca2+ [Golgi lumen]
Ca2+ [platelet dense tubular network lumen]
Ca2+ [platelet dense tubular network membrane]
Ca2+ [plasma membrane]
Ca2+ [secretory granule lumen]
Ca2+ [nucleoplasm]
Ca2+ [mitochondrial matrix]
Ca2+ [mitochondrial inner membrane]
Ca2+ [endoplasmic reticulum membrane]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Ca2+ [endoplasmic reticulum lumen]
Cross References
COMPOUND
C00076
PubChem Substance
8145461
HMDB Metabolite
HMDB0000464
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