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ICOSLG
Stable Identifier
R-HSA-197910
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
ICOSL, ICOS ligand precursor, ICOL_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Costimulation by the CD28 family (Homo sapiens)
ICOS binds ICOSL/B7-H2 (Homo sapiens)
ICOS:ICOSL [plasma membrane] (Homo sapiens)
ICOSLG [plasma membrane] (Homo sapiens)
ICOSLG [plasma membrane] (Homo sapiens)
PI3K binds ICOS (Homo sapiens)
ICOS:ICOSL [plasma membrane] (Homo sapiens)
ICOSLG [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75144 ICOSLG
Gene Names
ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Chain
signal peptide:1-18, chain:19-302
Reference Genes
BioGPS Gene:102723996 ICOSLG
BioGPS Gene:23308 ICOSLG
COSMIC (genes):ICOSLG ICOSLG
CTD Gene:23308 ICOSLG
dbSNP Gene:102723996 ICOSLG
dbSNP Gene:23308 ICOSLG
ENSEMBL:ENSG00000160223 ICOSLG
HGNC:17087 ICOSLG
KEGG Gene (Homo sapiens):hsa:102723996 ICOSLG
KEGG Gene (Homo sapiens):hsa:23308 ICOSLG
Monarch:102723996 ICOSLG
Monarch:23308 ICOSLG
NCBI Gene:102723996 ICOSLG
NCBI Gene:23308 ICOSLG
OMIM:605717 ICOSLG
UCSC:O75144 ICOSLG
Reference Transcript
RefSeq:NM_001283051.1 ICOSLG
RefSeq:NM_001283050.1 ICOSLG
RefSeq:XM_006723900.2 ICOSLG
RefSeq:NM_015259.5 ICOSLG
Other Identifiers
0006550162
11739295_a_at
11739296_a_at
16926302
211197_s_at
211198_s_at
211199_s_at
213450_s_at
228976_at
23308
26037
31803_at
3934409
3934410
3934411
3934412
3934413
3934414
3934415
3934416
3934417
3934418
3934422
3934424
3934425
3934426
3934427
3934428
3934430
57680_at
8070720
A0N0L8
A_23_P166280
A_23_P317667
A_23_P6272
AAF34739
AAG01176
AAH64637
AAK16241
ABK41909
BAA31628
BAF82881
BAG36999
BAG52170
CAB026037
CAC36465
CCDS42952
CCDS63377
CCDS63379
EAX09446
EAX09448
ENSG00000160223
ENSP00000339477
ENSP00000383228
ENSP00000384432
ENST00000344330
ENST00000400377
ENST00000407780
EntrezGene:23308
g6983943_3p_a_at
g9858866_3p_a_at
GE490101
GE528212
GE53364
GO:0002250
GO:0002376
GO:0005102
GO:0005886
GO:0006952
GO:0006972
GO:0007165
GO:0016020
GO:0016021
GO:0031295
GO:0042104
GO:0042110
GO:0042113
GO:0070062
HGNC:17087
Hs.14155.0.S3_3p_a_at
Hs.14155.2.S1_3p_a_at
Hs.65578.0.A1_3p_at
ICOSLG
ICOSLG-201
ICOSLG-202
ICOSLG-204
ILMN_1675671
K4DIA0
NM_001283050
NM_001283051
NM_001283052
NM_015259
NP_001269979
NP_001269980
NP_001269981
NP_056074
PF07686
PF08205
PH_hs_0001352
PH_hs_0004023
SM00409
TC21000516.hg
uc002zee.5
uc002zef.5
uc032qao.2
UPI000002ABA6
UPI0000049DCB
UPI00003E27DA
XM_011529514
XM_017028310
XP_011527816
XP_016883799
Participant Of
input
ICOS binds ICOSL/B7-H2
hasComponent
ICOS:ICOSL [plasma membrane]
Inferred To
ICOSLG [plasma membrane] (Bos taurus)
ICOSLG [plasma membrane] (Canis familiaris)
ICOSLG [plasma membrane] (Gallus gallus)
ICOSLG [plasma membrane] (Mus musculus)
ICOSLG [plasma membrane] (Rattus norvegicus)
ICOSLG [plasma membrane] (Sus scrofa)
ICOSLG [plasma membrane] (Taeniopygia guttata)
Cross References
RefSeq
XP_006723963.1
,
NP_056074.1
,
NP_001269979.1
,
NP_001269980.1
GeneCards
O75144
PRO
O75144
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y6W8 ICOS
0.611
3
UniProt:Q8WYB5 KAT6B
1
KAT6B [nucleoplasm]
(R-HSA-3318400)
0.488
2
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