Reactome | ICOSLG [plasma membrane]

ICOSLG [plasma membrane]

Stable Identifier

R-HSA-197910

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

ICOSL, ICOS ligand precursor, ICOL_HUMAN

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External Reference Information

External Reference

UniProt:O75144 ICOSLG

Gene Names

ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653

Chain

signal peptide:1-18, chain:19-302

Reference Genes

BioGPS Gene:23308 ICOSLG

COSMIC (genes):ICOSLG ICOSLG

CTD Gene:23308 ICOSLG

dbSNP Gene:23308 ICOSLG

ENSEMBL:ENSG00000160223 ICOSLG

HGNC:17087 ICOSLG

KEGG Gene (Homo sapiens):23308 ICOSLG

Monarch:23308 ICOSLG

NCBI Gene:23308 ICOSLG

OMIM:605717 ICOSLG

UCSC:O75144 ICOSLG

Reference Transcript

Other Identifiers

0006550162

0102680170

11739295_a_at

11739296_a_at

16926302

211197_s_at

211198_s_at

211199_s_at

213450_s_at

228976_at

23308

31803_at

3934404

3934406

3934408

3934409

3934410

3934411

3934412

3934413

3934414

3934415

3934416

3934417

3934418

3934422

3934424

3934425

3934426

3934427

3934428

3934430

57680_at

8070720

A_23_P166280

A_23_P317667

A_23_P6272

GE490101

GE528212

GE53364

GO:0001817

GO:0002250

GO:0002376

GO:0003674

GO:0005102

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005886

GO:0006950

GO:0006952

GO:0006972

GO:0007155

GO:0007165

GO:0008150

GO:0008283

GO:0009897

GO:0016020

GO:0016021

GO:0031295

GO:0036464

GO:0042104

GO:0042110

GO:0042113

GO:0042802

GO:0043226

GO:0050776

GO:0050852

GO:0070062

Hs.14155.0.S3_3p_a_at

Hs.14155.2.S1_3p_a_at

Hs.65578.0.A1_3p_at

ILMN_1675671

PH_hs_0001352

PH_hs_0004023

TC21000516.hg

g6983943_3p_a_at

g9858866_3p_a_at

Participant Of

input

ICOS binds ICOSL/B7-H2

hasComponent

ICOS:ICOSL [plasma membrane]

Inferred To

ICOSLG [plasma membrane] (Bos taurus)

ICOSLG [plasma membrane] (Canis familiaris)

ICOSLG [plasma membrane] (Gallus gallus)

ICOSLG [plasma membrane] (Sus scrofa)

Icoslg [plasma membrane] (Mus musculus)

Icoslg [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_006723963.1, NP_056074.1, NP_001269979.1, NP_001269980.1

OpenTargets

ENSG00000160223

HPA

ENSG00000160223-ICOSLG

GeneCards

O75144

Ensembl

ENST00000400377, ENSP00000384432, ENSP00000339477, ENSG00000160223, ENST00000344330, ENST00000407780, ENSP00000383228

PRO

O75144

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y6W8 ICOS			0.733	8
UniProt:O75144 ICOSLG	1	ICOSLG [plasma membrane] (R-HSA-197910)	0.672	7