Binding of the MYC:MAX heterodimer to MYC response elements in the first and second intron of the CDC25A gene activates CDC25A transcription in mid to late G1 (Galaktionov et al. 1996).Transcription of the CDC25A gene can be directly activated by E2F1 (DeGregori et al. 1995, Vigo et al. 1999).Transcription of the CDC25A gene is directly inhibited by the DREAM complex (Litovchick et al. 2007).
Galaktionov, K, Chen, X, Beach, D
Nevins, JR, DeGregori, J, Kowalik, T
DeCaprio, JA, Washburn, MP, Swanson, SK, Zhu, X, Florens, LA, Chen, R, Litovchick, L, Liu, XS, Sadasivam, S, Velmurugan, S
Hateboer, G, Vigo, E, Helin, K, Prosperini, E, Cartwright, P, Moroni, MC, Muller, H
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