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Virion with CD4 bound to gp120 [extracellular region]
Stable Identifier
R-HSA-173650
Type
Complex
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Early Phase of HIV Life Cycle (Homo sapiens)
Binding and entry of HIV virion (Homo sapiens)
Binding of gp120 of ENV oligomer to the host CD4 (Homo sapiens)
Virion with CD4 bound to gp120 [extracellular region] (Homo sapiens)
Conformational change in gp120 of Env oligomer (Homo sapiens)
Virion with CD4 bound to gp120 [extracellular region] (Homo sapiens)
Participants
components
CD4:gp120:gp41 membrane complex [plasma membrane]
(Homo sapiens)
HIV-1 RNA homodimer [extracellular region]
(Human immunodeficiency virus 1)
x 2
IN (Integrase) (P04585) protein [extracellular region]
(Human immunodeficiency virus 1)
Multimeric capsid coat [extracellular region]
(Human immunodeficiency virus 1)
Multimeric matrix layer [extracellular region]
(Human immunodeficiency virus 1)
myristoylated Nef Protein (UniProt:P04601) [extracellular region]
(Human immunodeficiency virus 1)
Nucleocapsid [extracellular region]
(Human immunodeficiency virus 1)
p6 protein [extracellular region]
(Human immunodeficiency virus 1)
PPIA [extracellular region]
(Homo sapiens)
PR (Protease) (P04585) protein [extracellular region]
(Human immunodeficiency virus 1)
REV (P04618) protein [extracellular region]
(Human immunodeficiency virus 1)
RT [extracellular region]
(Human immunodeficiency virus 1)
tRNA-Lysine3 [extracellular region]
(Homo sapiens)
VIF (P69723) protein [extracellular region]
(Human immunodeficiency virus 1)
VPR (P69726) protein [extracellular region]
(Human immunodeficiency virus 1)
VPU (P05919) protein [extracellular region]
(Human immunodeficiency virus 1)
Participates
as an output of
Binding of gp120 of ENV oligomer to the host CD4 (Homo sapiens)
as an input of
Conformational change in gp120 of Env oligomer (Homo sapiens)
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