Reactome | RPS6KB1-1 [cytosol]

RPS6KB1-1 [cytosol]

Stable Identifier

R-HSA-165716

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

p85 S6K1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P23443-1 RPS6KB1

Gene Names

RPS6KB1, STK14A

Participates

as a member of

RPS6KB1 [cytosol] (Homo sapiens)

Other forms of this molecule

p-T412-RPS6KB1-1 [cytosol]

Inferred To

RPS6KB1 [cytosol] (Canis familiaris)

RPS6KB1-1 [cytosol] (Bos taurus)

RPS6KB1-1 [cytosol] (Caenorhabditis elegans)

RPS6KB1-1 [cytosol] (Danio rerio)

RPS6KB1-1 [cytosol] (Dictyostelium discoideum)

RPS6KB1-1 [cytosol] (Drosophila melanogaster)

RPS6KB1-1 [cytosol] (Gallus gallus)

RPS6KB1-1 [cytosol] (Mus musculus)

RPS6KB1-1 [cytosol] (Rattus norvegicus)

RPS6KB1-1 [cytosol] (Saccharomyces cerevisiae)

RPS6KB1-1 [cytosol] (Schizosaccharomyces pombe)

RPS6KB1-1 [cytosol] (Sus scrofa)

RPS6KB1-1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_001258989.1, NP_001258971.1, NP_001258972.1, NP_001258973.1, NP_003152.1

ZINC - World Drugs

KS6B1_HUMAN

Guide to Pharmacology - Targets

1525

OpenTargets

ENSG00000108443

ENSEMBL

ENSP00000441993, ENST00000393021, ENSP00000384335, ENSP00000225577, ENSP00000376744, ENST00000225577, ENST00000406116, ENSG00000108443, ENST00000443572

ZINC - FDA approved

KS6B1_HUMAN

ZINC - Substances

KS6B1_HUMAN

ZINC - Biogenic

KS6B1_HUMAN

ZINC target

P23443

PRO

P23443

GlyGen

P23443

PDB

4L3L, 4RLO, 3A60, 3WF6, 4L46, 3A62, 5WBK, 3WF7, 4L45, 4L44, 3A61, 3WE4, 7N93, 5WBH, 3WF5, 4RLP, 3WF9, 4L3J, 4L43, 7N91, 4L42, 3WF8

ZINC - Investigational

KS6B1_HUMAN

IntEnz

2.7.11.1

HPA

ENSG00000108443-RPS6KB1

GeneCards

RPS6KB1

Pharos - Targets

P23443

ZINC - Predictions - Purchasable

KS6B1_HUMAN

HMDB Protein

HMDBP01426

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31749 AKT1	14	p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-S473-AKT1 [plasma membrane] (R-HSA-377265) AKT1 [plasma membrane] (R-HSA-199416) AKT1 [cytosol] (R-HSA-58252) p-T308-AKT1 [cytosol] (R-HSA-198634) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-S473-AKT1 [cytosol] (R-HSA-9841264) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [cytosol] (R-HSA-2219526) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.64	3
UniProt:Q13057 COASY	1	COASY [mitochondrial outer membrane] (R-HSA-196735)	0.544	4

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