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SUMF1:SUMF2 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-1614330
Type
Complex
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Glycosphingolipid catabolism (Homo sapiens)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Homo sapiens)
SUMF1:SUMF2 [endoplasmic reticulum lumen] (Homo sapiens)
SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases (Homo sapiens)
SUMF1:SUMF2 [endoplasmic reticulum lumen] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
The activation of arylsulfatases (Homo sapiens)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Homo sapiens)
SUMF1:SUMF2 [endoplasmic reticulum lumen] (Homo sapiens)
SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases (Homo sapiens)
SUMF1:SUMF2 [endoplasmic reticulum lumen] (Homo sapiens)
Participants
components
SUMF1 [endoplasmic reticulum lumen]
(Homo sapiens)
SUMF2 [endoplasmic reticulum lumen]
(Homo sapiens)
Participates
as an output of
SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases (Homo sapiens)
This entity regulates
Negatively
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases
(Homo sapiens)
Inferred To
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Bos taurus)
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Canis familiaris)
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Gallus gallus)
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Mus musculus)
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Rattus norvegicus)
SUMF1:SUMF2 [endoplasmic reticulum lumen]
(Sus scrofa)
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