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MMP14:TIMP2 [plasma membrane]
Stable Identifier
R-HSA-1604365
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Autocatalytic activation of bound proMMP2 (Homo sapiens)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP:MMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
Initial activation of proMMP2 by MMP14 (Homo sapiens)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2:proMMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
MMP14 (MT1-MMP) binds TIMP2 (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2 binds proMMP2 (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2:proMMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2 [plasma membrane] (Homo sapiens)
Participants
components
MMP14 [plasma membrane]
(Homo sapiens)
TIMP2 [extracellular region]
(Homo sapiens)
Participates
as a component of
MMP14:TIMP:MMP2 [plasma membrane] (Homo sapiens)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Homo sapiens)
MMP14:TIMP2:proMMP2 [plasma membrane] (Homo sapiens)
as an input of
MMP14:TIMP2 binds proMMP2 (Homo sapiens)
as an output of
MMP14 (MT1-MMP) binds TIMP2 (Homo sapiens)
Inferred To
MMP14:TIMP2 [plasma membrane]
(Bos taurus)
MMP14:TIMP2 [plasma membrane]
(Caenorhabditis elegans)
MMP14:TIMP2 [plasma membrane]
(Canis familiaris)
MMP14:TIMP2 [plasma membrane]
(Danio rerio)
MMP14:TIMP2 [plasma membrane]
(Drosophila melanogaster)
MMP14:TIMP2 [plasma membrane]
(Mus musculus)
MMP14:TIMP2 [plasma membrane]
(Rattus norvegicus)
MMP14:TIMP2 [plasma membrane]
(Sus scrofa)
MMP14:TIMP2 [plasma membrane]
(Xenopus tropicalis)
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