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MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
Stable Identifier
R-HSA-1604373
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
Activation of Matrix Metalloproteinases (Homo sapiens)
Autocatalytic activation of bound proMMP2 (Homo sapiens)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Homo sapiens)
Initial activation of proMMP2 by MMP14 (Homo sapiens)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane] (Homo sapiens)
Participants
components
MMP14:TIMP2 [plasma membrane]
(Homo sapiens)
MMP2(67-660) [extracellular region]
(Homo sapiens)
Participates
as an input of
Autocatalytic activation of bound proMMP2 (Homo sapiens)
as an output of
Initial activation of proMMP2 by MMP14 (Homo sapiens)
Inferred To
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Bos taurus)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Caenorhabditis elegans)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Canis familiaris)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Danio rerio)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Drosophila melanogaster)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Mus musculus)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Rattus norvegicus)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Sus scrofa)
MMP14:TIMP2:MMP2 intermediate form [plasma membrane]
(Xenopus tropicalis)
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