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CLEC10A [plasma membrane]
Stable Identifier
R-HSA-1472863
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-type lectin domain family 10 member A, CLC10_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
Dectin-2 family (Homo sapiens)
CLEC10A binds Tn-MUC1 (Homo sapiens)
CLEC10A [plasma membrane] (Homo sapiens)
CLEC10A:Tn antigens [plasma membrane] (Homo sapiens)
CLEC10A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IUN9 CLEC10A
Gene Names
CLEC10A, CLECSF13, CLECSF14, HML
Chain
chain:1-316
Reference Genes
BioGPS Gene:10462 CLEC10A
COSMIC (genes):CLEC10A CLEC10A
CTD Gene:10462 CLEC10A
dbSNP Gene:10462 CLEC10A
ENSEMBL:ENSG00000132514 CLEC10A
ENSEMBL_homo_sapiens_GENE:ENSG00000132514.14 CLEC10A
HGNC:16916 CLEC10A
KEGG Gene (Homo sapiens):10462 CLEC10A
Monarch:10462 CLEC10A
NCBI Gene:10462 CLEC10A
OMIM:605999 CLEC10A
UCSC:Q8IUN9 CLEC10A
Reference Transcript
RefSeq:NM_006344.3 CLEC10A
RefSeq:NM_182906.3 CLEC10A
Other Identifiers
10462
11740531_a_at
11745500_a_at
11760018_at
16840473
206682_PM_at
206682_at
33569_at
3743312
3743313
3743314
3743315
3743316
3743317
3743318
3743319
3743320
3743321
3743322
3743323
3743324
3743325
3743326
3743327
3743328
3743329
8012013
A_23_P141505
A_23_P141508
D50532_at
GE81625
GO:0002250
GO:0002376
GO:0005515
GO:0005537
GO:0005886
GO:0006897
GO:0009897
GO:0016020
GO:0016192
GO:0030246
GO:0042806
GO:0045087
GO:0098542
ILMN_1653166
ILMN_1704797
ILMN_2415303
PH_hs_0003557
PH_hs_0035431
TC17001074.hg
g5453683_3p_at
Participates
as a component of
CLEC10A:Tn antigens [plasma membrane] (Homo sapiens)
as an input of
CLEC10A binds Tn-MUC1 (Homo sapiens)
Inferred To
tfc [plasma membrane]
(Drosophila melanogaster)
clec-196 [plasma membrane]
(Caenorhabditis elegans)
clec-266 [plasma membrane]
(Caenorhabditis elegans)
lectin-37Da [plasma membrane]
(Drosophila melanogaster)
LOC116412330 [plasma membrane]
(Xenopus tropicalis)
cldc1 [plasma membrane]
(Danio rerio)
CLEC10A [plasma membrane]
(Bos taurus)
CLEC10A [plasma membrane]
(Caenorhabditis elegans)
CLEC10A [plasma membrane]
(Gallus gallus)
lectin-24Db [plasma membrane]
(Drosophila melanogaster)
lectin-21Ca [plasma membrane]
(Drosophila melanogaster)
lectin-29Ca [plasma membrane]
(Drosophila melanogaster)
clec-91 [plasma membrane]
(Caenorhabditis elegans)
clec-199 [plasma membrane]
(Caenorhabditis elegans)
asgr1a [plasma membrane]
(Danio rerio)
lectin-24A [plasma membrane]
(Drosophila melanogaster)
clec-47 [plasma membrane]
(Caenorhabditis elegans)
nw [plasma membrane]
(Drosophila melanogaster)
clec-87 [plasma membrane]
(Caenorhabditis elegans)
clec-86 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG12111 [plasma membrane]
(Drosophila melanogaster)
Sfp24F [plasma membrane]
(Drosophila melanogaster)
si:ch211-125e6.13 [plasma membrane]
(Danio rerio)
BEST:GH10831 [plasma membrane]
(Drosophila melanogaster)
clec-149 [plasma membrane]
(Caenorhabditis elegans)
clec-224 [plasma membrane]
(Caenorhabditis elegans)
clec-204 [plasma membrane]
(Caenorhabditis elegans)
CR14499 [plasma membrane]
(Drosophila melanogaster)
Dmel\CG14500 [plasma membrane]
(Drosophila melanogaster)
clec-88 [plasma membrane]
(Caenorhabditis elegans)
clec-202 [plasma membrane]
(Caenorhabditis elegans)
Dmel\CG14866 [plasma membrane]
(Drosophila melanogaster)
clec-45 [plasma membrane]
(Caenorhabditis elegans)
lectin-21Cb [plasma membrane]
(Drosophila melanogaster)
Dmel\CG15818 [plasma membrane]
(Drosophila melanogaster)
Lectin-galC1 [plasma membrane]
(Drosophila melanogaster)
lectin-22C [plasma membrane]
(Drosophila melanogaster)
Dmel\CG43055 [plasma membrane]
(Drosophila melanogaster)
Homologues of CLEC10A [plasma membrane]
(Caenorhabditis elegans)
Homologues of CLEC10A [plasma membrane]
(Danio rerio)
Homologues of CLEC10A [plasma membrane]
(Drosophila melanogaster)
Homologues of CLEC10A [plasma membrane]
(Gallus gallus)
lectin-37Db [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_006335.2
,
NP_878910.1
OpenTargets
ENSG00000132514
GeneCards
Q8IUN9
HPA
ENSG00000132514-CLEC10A
Ensembl
ENSP00000254868
,
ENSP00000458728
,
ENSP00000460252
,
ENSG00000132514
,
ENST00000571664
,
ENST00000254868
,
ENST00000576617
PRO
Q8IUN9
Pharos - Targets
Q8IUN9
HMDB Protein
HMDBP07587
PDB
6PY1
,
6XIY
,
6PUV
,
6W12
Interactors (25)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WWP7 GIMA1
0.601
4
UniProt:Q13021 MALL
0.556
3
UniProt:O60831 PRAF2
0.556
3
UniProt:Q96MV8 ZDH15
0.556
3
UniProt:Q9NWW5 CLN6
0.556
3
UniProt:Q9NRQ5 SMCO4
0.556
3
UniProt:Q9H115 NAPB
1
NAPB [cytosol]
(R-HSA-5688553)
0.556
5
UniProt:P30536 TSPO
1
TSPO [mitochondrial outer membrane]
(R-HSA-2980957)
0.556
3
UniProt:Q5BVD1 TTMP
0.556
3
UniProt:A2RU14 TM218
0.556
3
UniProt:Q96IW7 SEC22A
3
SEC22A [ER to Golgi transport vesicle membrane]
(R-HSA-5688560)
SEC22A [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688562)
SEC22A [endoplasmic reticulum membrane]
(R-HSA-5216111)
0.556
3
UniProt:Q53HI1 UNC50
0.556
3
UniProt:A5PKU2 A5PKU2
0.556
3
UniProt:Q15848 ADIPOQ
1
ADIPOQ [extracellular region]
(R-HSA-1183052)
0.556
3
UniProt:P05090 APOD
1
APOD [extracellular region]
(R-HSA-5216199)
0.556
3
UniProt:Q96CM8 ACSF2
1
ACSF2 [mitochondrial matrix]
(R-HSA-5696005)
0.556
3
UniProt:Q9NVC3 S38A7
0.556
3
UniProt:P01375 TNF
5
TNF(52-76) [extracellular region]
(R-HSA-8863375)
TNF(1-34) [plasma membrane]
(R-HSA-8863367)
TNF(1-76) [plasma membrane]
(R-HSA-8863120)
TNF(77-233) [extracellular region]
(R-HSA-976821)
TNF(1-233) [plasma membrane]
(R-HSA-66220)
0.556
3
UniProt:O15155 BET1
3
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688142)
BET1 [transport vesicle]
(R-HSA-6808719)
BET1 [Golgi membrane]
(R-HSA-6807743)
0.556
3
UniProt:O95159 ZFPL1
0.556
3
UniProt:Q6UX27-3 VSTM1
0.556
3
UniProt:P31513 FMO3
6
FMO3 M66I [endoplasmic reticulum membrane]
(R-HSA-5603010)
FMO3 E32K [endoplasmic reticulum membrane]
(R-HSA-5602848)
FMO3 R492W [endoplasmic reticulum membrane]
(R-HSA-5602849)
FMO3 N61S [endoplasmic reticulum membrane]
(R-HSA-5602964)
FMO3 P153L [endoplasmic reticulum membrane]
(R-HSA-5602837)
FMO3 [endoplasmic reticulum membrane]
(R-HSA-54929)
0.556
3
UniProt:Q9H0Q3 FXYD6
1
FXYD6 [plasma membrane]
(R-HSA-2752104)
0.556
3
UniProt:Q9Y5Y5 PEX16
2
PEX16 [peroxisomal membrane]
(R-HSA-9603805)
PEX16 [cytosol]
(R-HSA-9603790)
0.556
3
UniProt:Q8N8J7 F241A
0.499
2
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